GIANT CELL TUMOUR Flashcards
DEFINE
CONSISTS OSTEOCLAST TYPE GIANT CELL ( HAVING 100 OR MORE NUCLEI ) , GIANT CELL BELIEVE DTO FORM BY FUSION OF MONOCYTES
PATHOLOGY
GROSS
MICROSCOPIC
AGE
20 TO 40 YEARS
GROSS
EPIPHYSEAL END OF BONE ENLARGED TO ONE SIDE
TUMOUR MAYE BE RED OR BROWN
NO PERIOSTEAL NEW BONE FORMATION
INNER WALL OF TUMOUR LINED BY FIBROUS CAPSULE FROM WHICH SEPTA ARISE WHICH PARTITIONS THE BONE
MICROSCOPY
UNDIFFERENTIATED SPINDLE CELLS WITH MULTINUCLEATED GIANT CELL
SEX
MALE
SITE
AROUND KNEE AND LOWER END OF RADIUS
LOCATION
EPIPLYSIS IN ADULT
METAPHYSIS IN CHILDREN
RADIOGRAPH
SOLITARY , LYTIC LESION
ECCENTRIC LOCATION NEAR EPIPHYSIS
SOAP BUBBLE APPEARANCE
NO ERIOSTEAL NEW BONE FORMATION
THINNED CORTEX
JOINT NOT INVOLVED
CLINICAL FEATURES
NO PAIN
HISTORY OF TRAUMA
SWELLING ON ONE SIDE OF BONE
SKIN STRETCHED , NO DIALATED VEINS
IF PATHOLOGICAL # PRESENT = DEFORMED LIMB
TREATMENT
EXCISION
EXCISION AND REPLACED BY VASCULARISED BONE GRAFT
EXCISION WITH RECONSTRUCTION
CURRETAGE WITH OR WITHOUT SUPLEMENTARY PROCEDURE
AMPUTATION
RADIOTHERAPY
EXCISION WITH RECONSTRUCTION
ARTHRODESIS BY TURN O PLASTY PROCEDURE
ARTHRODESIS BY BRIDGING THE GAP
ARTHROPLASTY USING ALLOGRAFT , AUTOGRAFT OR PROSTHESIS
CURRETAGE WITH OR WITHOUT SUPPLEMENTARY PROCEDURE
ONLY CURETTAGE
CRYOTHERAPY WITH LIQUID NITROGEN
CHEMICAL CAUTERY BY PMMA
BONE GRAFTING