GI Tract (Exam III) Flashcards
Name of canal that extends from oral cavity to anus
Alimentary canal
Five phases of food breakdown:
1- ingestion
2- fragmentation
3- digestion
4- absorption
5- elimination
_____ occurs in the oral cavity, accompanied by _____; resulting in ____ formation
ingestion; fragmentation, bolus
Stomach completes ______ & initiates ______
fragmentation; digestion
Contractions of smooth in GI system
peristalsis
Peristalsis occurs under the control of:
Autonomic control
In the duodenum, what do pancreatic & biliary secretions do?
Emulsification of fat
Where does emulsification of fat occur?
In duodenem
What occurs in the jejunum & ileum?
Primary absorption of nutrients
What occurs in the colon?
respiration of water & elimination of waste
The muscular tube of the GI tract is lined by:
Mucus membrane
There are a large number of ____ associated with the GI tract
glands
List three glands of the GI tract
1- liver glands
2- pancreas glands
3- intestinal glands
The liver, pancreas, & intestinal glands all have what in common?
All embryological outgrowths of the GI tract
Diffuse lymphoid tissue scattered throughout the GI tract
MALT
GALT
What are the four distinct layers of the GI tract?
1- mucosa
2- submucosa
3- muscularis externa
4- adventitia (serosa)
The mucosa has three overall functions including:
1- protection
2- secretion
3- absorption
Different types of mucosa are modified for:
Different functions
The mucosa of the GI tract is subdivided into three layers including:
1- epithelium
2- lamina propria
3- muscularis mucosae
Layer of mucosa that has secretory & absorptive functions
epithelium
the ____ layer of the mucosa has different modifications at different levels of the GI tract
epithelium
Layer of mucosa -thin underlying connective tissue layer
lamina propria
What are some components of the lamina proprietary (4):
1- lymphoid nodules
2- glands
3- blood vessels
4- lymphatics
Layer of mucosa- thin layer of smooth muscle
muscularis mucosae
The layer mucosa that acts as a boundary between the mucosa & submucosa
muscularis mucosae
What does the muscularis mucosae act as a boundary between?
mucosa & submucosa
Large numbers of ____ & ____ cells in the lamina propria
Lymphocytes & plasma cells (immune surveillance)
Layer of the gut- loose to dense irregular connective tissue layer beneath the muscularis mucosae
submucosa
Layer of the gut responsible for supporting the mucosa
submucosa
List the components of the submucosa
larger blood vessels, nerves & lymphatics
inner circular & outer longitudinal smooth muscle layers of the gut
muscularis externa
The muscularis externa may also be called
muscularis propria
The smooth muscle fibers of the muscularis externa are oriented at:
right angles to one another
The inner circular layer of the muscularis externa (propria) contains fibers:
fibers going circumferential around the gut
The outer longitudinal layer of the muscularis externa contains:
muscle fibers oriented at right angles to one another
The local contractions that result in mixing of food in the gut
segmentation
Segmentation occurs both ____ & ____ in either direction
proximally & distally
Propels food only in the distal direction
peristalsis
Overall effect is like kneading bread dough that results in mixing food with digestive secretions but NOT pushing food down the gut
segmentation
When talking about peristalsis another term we can use the direction that the food is pushed is _____ which means ____
aborally- meaning away from mouth toward anus
Describe the contractions of peristalsis
Forceful & organized
Outer loose connective tissue layer of the gut that contains major nerves, vessels & adipose tissue
adventitia
The adventitia within the abdominal cavity is referred to as:
serosa or visceral perioteneum
The adventitia in the gut (serosa/visceral peritoneum) is continuous with:
supporting mesentary
The adventitia of the gut (serosa/visceral peritoneum) is lined by:
simple squamous epithelium (mesothelium)
In other areas, the adventitia (serosa/visceral peritoneum) merges with:
retroperitoneal tissue
The smooth & shiny surface of the gut
adventitia (serosa/visceral peritoneum)
The smooth muscle of the gut is controlled by:
the autonomic nervous system
the parasympathetic stimulation of the smooth muscle of the gut results in:
excitatory
the sympathetic stimulation of the smooth muscle of the gut results in:
inhibitory
The parasympathetic motor nerves synapse with:
ganglia located near the effector organ
Parasympathetic nerves synapse with:
ganglia near the effector organ
in the GI tract, ganglia are located:
within the wall of gut (within submucosa & muscularis externa)
Clusters of parasympathetic ganglia within the submucosa:
Meissner’s plexus (submucosal plexus)
What type of ganglia comprise the meissner’s plexus:
parasympathetic
Larger clusters of ganglia located between inner circular & outter longitudinal muscular layers:
myenteric or Auerbachs plexus
Short, muscular tube lined by stratified squamous nonkeratinized epithelium
esophagus
What type of cells line the esophagus
stratified squamous nonkeratinized epithelium
In the upper third of the esophagus, the muscular externa is composed of:
The middle third of the esophagus is composed of:
The lower third of the esophagus is composed of:
voluntary skeletal muscle
skeletal & smooth muscle
smooth muscle only
Due to the muscle makeup of the esophagus swallowing occurs in the upper third made of ______ muscle so it is ______. Vomiting occurs in the lower one third of esophagus so it is ______
skeletal muscle; voluntary
smooth muscle; involuntary
Where is the gastropesophageal sphincter located?
gastroesophageal junction between the stomach & esophagus
heartburn:
pyrosis
pyrosis is due to regurgitation of _____ into the ______ from the cardia from the ____ of the stomach
stomach acid
distal esophagus
cardia
Regions of the stomach (3):
1- cardia
2- fundus
3- pylorus
The cardia is surrounded by a:
smooth muscle cardiac sphincter
the smooth muscle cardiac sphincter that surrounds the cardia is known as the:
gastropesophageal sphincter
Adjacent to the esophagus- contains predominantly muscous-secreting glands
cardiac sphincter (gastroesophageal sphincter)
The glandular portion of the stomach
fundus
the funds secretes (3)
1- acid
2- pepsin
3- some mucous
Some texts differentiate the fundus from the ______
Both are glandular but the fundus is closer to the _____ & the ____ is closer to the _____
corpus
cardia
corpus; pylorus
Part of the stomach containing primarily mucous & gastrin secreting glands
pylorus
The smooth muscle ______ controls outflow from the stomach into the duodenem
pyloric sphincter
Loss of stomach/duodenal epithelium/mucosa
peptic/gastric ulcer
an ulcer occurs when damage extends below the level of the _____ & ______ leading to bleeding
basement membrane & lamina propria
partial loss of the epithelium in the stomach but does not lead to bleeding
erosion
what is the treatment for peptic/gastric ulcers
antacids, Tagamet, cimetidine
the term peptic ulcers houses:
stomach & duodenal ulcers
ulcers are frequently associated with:
chronic infection with helicobacter pylori
Helicobacter pylori produce ____ resulting in _____ & secondarily leading to _____
urease; increased gastric pH; increased acid production
Treatment of helicobacter pylori includes:
Triple therapy
The triple therapy used to treat helicobacter pylori includes:
two long-term antibiotic & proton pump inhibitor
Distensible organ used for food storage
stomach
how many chambers does the stomach have in most animals?
one
in the stomach food undergoes mechanical breakdown via ___ & chemical breakdown via _____ to form _____
muscular activity
gastric secretions
chyme
In addition to the inner circular & outer longitudinal layers of the stomach, there is also a:
Third inner oblique layer in the muscular exrterna
little ______ occurs in the stomach
what are the exceptions:
absorption
water, alcohol, & some drugs (aspirin)
the stomach lining contains prominent longitudinal folds called:
rugae
In the glandular body of the stomach (fundus), mucosa contains prominent:
gastric pits called foveolae
The gastric pits in the mucosa (foveolae) of the fundus forms the entrance to:
gastric glands
The gastric glands of the fundus are:
straight tubular glands
The gastric glands of the stomach secrete around:
2 liters of watery gastric juice/day
The watery gastric juice secreted by the gastric glands of the stomach contains:
(what makes up the gastric juice & at what pH)
1- HCL (pH=1)
2. Pepsinogen
Pepsinogen is an ______ of _______
inactive precursor of pepsin
Pepsinogen is converted to pepsin by the action of:
HCL
In addition to the pepsinogen & HCL what other components are found in the gastric juices of the stomach:
gastrin
rennin
lipase