GI Physiology Flashcards
The liver can regenerate up to how much?
70%
Layers of the GI tract
Mucosa; submucosa, muscularis, serosa
Where are ito cells found
Space of disse
Where are kuppfer cells found
Liver sinusoids
Cells in the liver that store vit A
Ito cells
APC cells in the liver
Kuppfer cells
Source of gastrin
G cells
Source of secretin
S cells
Source of cholecysokinin
I cells
Source of glucose dependent insulinotrophic pepide
K cells
Source of motilin
M cells
Increases gastric H secretion, stimulates growth of gastric mucosa
Gastrin
Increases pancreatic bicarbonate, increases biliary bicarbonate; decreases effect of gastrin
Secretin
Stimulates GB contraction, sphincter of oddi relaxation; inhibits gastric emptying
CCK
Increases insulin secretion, inhibits gastric emptying
Glucose dependent insulontrophic enzyme
Removed remnant food in GI tract
Motilin
Most potent stimuli for gastrin production
Tryptophan, phenylalanine, methionine
Candidate GI hormone that inhibits pancreatic HCO3 and enzymes
Pancreatic polypeptide
GLP 1 is secreted by?
L cells
Candidiate GI hormone that stimulates insulin production
GLP 1
Inhibits release of all GI hormones
Somatostatin
Increases H secretion; potentiates gastrin and Ach action
Histamine
NT that increases salivary secretion
NE
Contractions due to subthreshold slow waves
Tonic contractions
Contractions due to spike potentials
Phasic contractions
GI pacemaker
Intersititial cells of cajal
Spike potential’s depolarization is due to
Calcium
Receptive relaxation of the orad stomach is due to
Vagovagal reflex mediated by VIP
Responsible for migrating myoelectric complex
Motilin
