GI Pathology Flashcards
The histologic diagnosis of Barrett’s esophagus is based on
A. Replacement of squamous mucosa by glandular mucosa
B. Glandular hyperplasia with active inflammation
C. Intestinal goblet cells in the glandular mucosa
D. Presence of glandular dysplasia
C
The most common primary neoplasm of the appendix is A. Mucinous cystadenoma B. Carcinoid C. Mucoceole D. Lymphoma
B
Meckel’s diverticulum may cause/be A. Peptic ulcer disease of the ileum B. Intussuception C. Asymptomatic D. AOTA
D
In the western world, the most common cause of cirrhosis is A. Alcoholic liver disease B. Viral hepatitis C. Biliary disease D. Alpha-1 antitrypsin deficiency
A
In the Philippines, B is the most common followed by A. Other causes are primary
hemochromatosis and Wilson’s disease.
The clinical course of Rotor syndrome (complete name Rotor-Manahan-Florentin syndrome)
is
A. Demise during childhood
B. Demise in early adulthood
C. Intermittent episodes of hepatic failure
D. Innocuous
D
In chronic hepatitis, the hallmark of irreversible liver damage is
A. Hepatocyte necrosis involving 70% of liver mass
B. The deposition of fibrous tissue
C. Predominantly conjugated hyperbilirubinemia
D. Predominantly unconjugated hyperbilirubinemia
B
Mallory bodies may be seen in A. Alcoholic liver disease B. Wilson’s disease C. Hepatocytes with denaturated cytokeratin intermediate filament D. AOTA
D
The so-called “bile duct proliferation” in the liver is
A. A pre-neoplastic phenomenon
B. A direct effect of cirrhosis
C. The biliary system’s attempt at reducing increased intraductal bile pressure
D. An histologic evidence of unconjugated hyperbilirubinemia
C
This occurs when the bile duct is obstructed for whatever reason, causing bile to accumulate in it.
The duct then becomes tortuous, resulting in seemingly multiple ducts upon cross-section
A histologic differential diagnosis of cholangiocarcinoma
A. Klatskin tumor
B. Metastatic pancreatic duct CA to the liver
C. Hepatic adenoma
D. Metastatic alveolar cells CA of the pancreas
B
The more common type of gallbladder stone in Asia is A. Predominantly cholesterol B. Predominantly pigment C. Predominantly fat D. All occur in equal frequency
B
Most common primary site of carcinoid tumor A. Esophageal stomach B. Small intestine C. Appendix D. Colon and rectum
C
The etiopathogenesis behind classic pancreatitis is
A. Oversecretion of pancreatic enzymes
B. Premature activation of pancreatic enzymes
C. Obstruction of pancreatic duct
D. Underdigestion due to undersecretion of pancreatic enzymes
B
Most common location of squamous cell CA of the esophagus A. Proximal third B. Middle third C. Distal third D. Equal distribution
B
The definitive liver biopsy feature of extrahepatic biliary atresia is
A. Bile duct proliferation
B. Bile duct destruction
C. Parenchymal hepatocellular cholestasis
D. Portal tract edema and fibrosis
A
True of Gastrointestinal Stromal Tumor (GIST) EXCEPT
A. Arises from the Cajal cell
B. Typically an intramural tumor
C. Is CD 117 positive all the time
D. CD 117 positive tumors will usually respond to therapy (“Gleevec”)
C?
