GI Bleeding and Pancreatitis Flashcards
Mortality score for admitted patients with upper GI bleeding
AIMS65
Components of the AIMS65 score
Albumin INR Mental status (altered) SBP Age (<65)
Albumin cut off for AIMS65 score
< 3.0
INR cut off for AIMS65 score
> 1.5
BP cut off from AIMS65 score
< 90
Maximum AIMS65 score and mortality risk
5
100%
AIMS65 score of 4 mortality risk
75%
AIMS65 score 3 mortality risk
43%
Step that comes before sending patient for EGD
Volume resuscitation
Time frame for EGD in GI bleeding patient
Within 24 hours (No benefit in any earlier)
SHOCK EXCLUDED IN STUDIES
“Benign” GI bleeding endoscopic key word findings
Clean based or flat pigmented spot
Transfusion goal in GI bleeding
< 7 UNLESS ACTIVELY BLEEDING
Bolus or drip for PPI in GI bleeding?
Bolus (non inferior in studies)
Dose of Octreotide for variceal bleeding
50 mcg bolus followed by 50 mcg/hr for 3-5 days after hemostasis
Antibiotic class preferred in variceal bleeding
quinolones
Banding vs sclerotherapy for variceal bleeding, which is superior?
Banding
Tube used in severe upper GI bleeding
Blakemore or Minnesota tube
Catastrophic complication of placement of a blakemore tube
Esophageal rupture
4 contraindications to TIPS procedure
CHF
Severe PHTN
Systemic infection/sepsis
Severe TR
Ligament that anatomically defines upper vs lower GI bleeding
Ligament of treitz
Purge preparation routine dosing
4-6L of polyethylene glycol
Most sensitive test for lower GI bleeding
Radionucleotide imaging
not great at localization of the bleeding
Diagnostic and therapeutic intervention for lower GI bleeding that can’t undergo scope
Angiography (can localize and embolize)
Diarrhea definition for C diff
> 3 loose stools in 24 hours
Toxin A or B, which strain causes the symptoms in Cdiff?
Toxin B
2 Criteria for severe C diff infection
WBC > 15K
OR
Cr > 1.5
3 Criteria for fulminant C diff
Hypotension/Shock
Ileus
Megacolon
Treatment regimen for non-fulminant C diff infection
Vancomycin 125 mg q6h for 10 days
OR
Fidaxomicin 200 mg BID for 10 days
Treatment for fulminant C diff infection
Vancomycin 500 mg q6h
Flagyl 500 mg q8h
Discoloration of the sides of the abdomen
Grey turner sign in pancreatitis
3 criteria to diagnose acute pancreatitis
Abdominal pain consistent with pancreatitis
Amylase or lipase > 3x upper limit
Characteristic imaging findings
need 2 of the 3
BISAP score for pancreatitis components
BUN Impaired mental status SIRS Age Pleural effusion
Score in pancreatitis that can estimate mortality
BISAP score
BUN cut off for BISAP score
BUN > 25
AGE cut off for BISAP score
Age > 60
Are routine antibiotics administered in acute pancreatitis?
No
Treatment of choice for infected necrosis in acute pancreatitis
Carbapenem
Triglyceride level that can cause acute pancreatitis
> 1000
Enteric or parenteral feedings in acute pancreatitis
enteric
Bolus or goal directed IV fluids in acute pancreatitis
goal directed