GI 4C- Large intestine Flashcards

1
Q

Fibers of the large intestines external muscular layer are collected into longitudinal bands called____

A

teniae coli

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2
Q

Formation of outpouchings between teniae

A

haustra

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3
Q

The mucosa of the large intestines lacks

A

villi

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4
Q

Parts that compose the colon

A

cecum, ascending colon, hepatic flexure, transverse colon, splenic flexure, descending colon, sigmoid colon, rectum

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5
Q

Absorptive, Goblet, Endocrine and regenerative cells compose the______ in the intestines

A

Crypts of Lieberkuhn

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6
Q

Basic functions of the large intestines

A

Propulsion and storage of unabsorbed material, home to flora, absorb water and electrolytes, defecation

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7
Q

How many species of bacteria are found in the large intestines?

A

500

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8
Q

Established roles of intestinal flora include:

A
  1. Fermentation of undigestible dietary fiber to generate fatty acids 2. Create environment inhospitable to pathogens 3. metabolism of various compounds 4. Creation of Vitamin K, B12 and folic acid
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9
Q

What is the pH of poo

A

5.0-7.0

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10
Q

Diarrhea is caused by 4 distinct mechanisms:

A
  1. increased osmotic load 2. increased secretion 3. inflammation 4. decreased absorption time
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11
Q

This occurs when unabsorbable, water-soluble solutes remain in the bowel, where they retain water

A

osmotic diarrhea

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12
Q

What can cause osmotic diarrhea

A

sugar intolerance, poorly absorbed salts, certain fruits

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13
Q

This occurs when the small and large bowel secrete more electrolytes and water than they absorb

A

secretory diarrhea

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14
Q

What can cause secretory diarrhea

A

bacterial toxins, enteropathogenic viruses, bile acids, unabsorbed dietary fat

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15
Q

This occurs with several mucosal diseases that cause mucosal inflammation, ulceration or tumefaction. This results in increased fecal bulk and fluid content

A

exudative diarrhea

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16
Q

decreased absorption time

A

When chyme is not in contact with an adequate absorptive surface of the GI tract so that too much water remains in the feces

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17
Q

What happens when your best friend puts too much exlax in your drink?

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18
Q

Common causes of constipation

A

failure to poop when prompted, poor fiber, poor hydration, weak abdominal muscles, pregnancy, hemorrhoids

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19
Q

Which drugs cause constipation

A

opiates, anti-cholinergic agents, calcium channel blockers, diuretics, iron supplements, antacids

20
Q

GI disorder characterized by a variable combination of chronic and recurrent intestinal symptoms

A

irritable bowl syndrome

21
Q

What is the hallmark of IBS

A

abdominal pain relieved by defection and a change in consistency or frequency of stools

22
Q

What is believed to cause IBS

A

dysregulation of intestinal motor and sensory functions modulated by the CNS

23
Q

Where can the cobble stone appearing mucosa appear

A

Intestines and mouth

24
Q

What do flatulence of a patient with IBS sound like

25
Inflammatory bowl disease is used to designate two related inflammatory intestinal disorders _____ and \_\_\_\_\_\_
Crohn disease and ulcerative colitis
26
What are the similarities between Crohn's disease and ulcerative colitis
produce inflammation of the bowel, lack confirming evidence of a proven causative agent, can be accompanied by systemic manifestations
27
Crohn disease has _____ lesions
Skip lesions
28
A condition in which the mucosal layer of the colon herniates through the muscularis layer from high intraluminal pressure
diverticulosis
29
What is trapped in the colon for patients with diverticulosis
diverticula
30
Diverticulitis
inflammed diverticula
31
Diverticulitis most common symptoms
lower LEFT quadrant pain, nausea, vomiting
32
Acute appendicitis
inflammation of the veriform appendix due to an obstruction with stool or a twisting of the organ or its blood supply
33
Complaints associated with acute appendicitis
lower RIGHT quadrant pain, fever
34
appendix bursts causing
peritonitis
35
4 major mechanical causes of intestinal obstructions
1. herniation of a segment in the umbilical or inguinal 2. adhesion between loops of intestines 3. volvulus 4. intussusception
36
does the defecation reflex involve the brain?
no
37
defecation reflex
spinal cord mediated parasymp reflex that causes the walls of the sigmoid colon and the rectum to contract and the internal anal sphincter to relax
38
GI tract bleeding can be evidence of:
trauma to GI structures, blood vessel abnormalities or disorders in blood clotting.
39
Blood in the vomitus
hematemesis
40
Bright red stool means bleeding is in
lower GI
41
passage of black and tarry stools
melena
42
Tarry stools usually indicate that the source of bleeding is
above the level of the ileocecal valve
43
blood in stool only detected by chemical means
occult
44
One of the most common cancers in the Western world
adenocarcinoma of the colon and rectum
45
What are predisposing factors for colon cancer
polyps, long-standing UC, genetic factors, low fiber diet