Genomic sequencing Flashcards
What is genomics?
The study of genomes.
What is genomic sequencing?
Working out the sequence of nucleotide bases in a gene or genome.
What is bioinformatics?
The use of computers and statistical analysis to compare sequence data.
What are three types of organisms which have had their genome sequences?
Pest species, viruses and model organisms.
What is phylogenetics?
The study of evolutionary relatedness.
What was the order of evolution of life on earth?
Last universal ancestor, prokaryotes, photosynthesis, eukaryotes, multicellular organisms, invertebrates, vertebrates, land plants
How can we work out the sequence of evolution of life on Earth?
Using sequence data and fossil evidence.
How is a molecular clock constructed?
By comparing the number of differences in organisms genomes you can work out how long since they have diverged.
How could differences in DNA sequences tell you how distantly related two organisms are?
The more differences in the DNA sequences the more distantly related.
What is pharmacogenetics?
The use of a persons genome to prescribe personalised medicine.
What are the three domains of life?
Archea, bacteria, eukaryotes
What is a possible ethical issue of medical genomic sequencing?
Employers may be biased, insurance companies may be biased, could worry family members
Which order did the three domains of life evolve in?
Bacteria, archae, eukaryotes
What are the medical benefits of genomic sequencing?
Knowledge of disease risk, prescribe suitable drugs at the correct dosage.
