Genital ulcers Flashcards

1
Q

Causes of genital ulcers

A

Herpes simplex virus 1 and 2
Syphilis
Chancroid

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2
Q

Herpes simplex virus 1 presentation

A

Cold sores
Chills
Muscle ache
Dysuria

Can spread to genitals if oral sex:
Vulval soreness
Vulval blisters and ulcers

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3
Q

Herpes simplex virus 2 presentation

A
Vulval soreness 
Vulval blisters and ulcers 
Chills 
Muscle ache 
Dysuria
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4
Q

HSV1

  • presentation
  • seropositivity
  • recurrence in 1 year
  • recurrence after year 1
A
  • Orofacial
  • 80% seropositive
  • 60% recurrence
  • unusual
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5
Q

HSV2

  • presentation
  • seropositivity
  • recurrence in 1 year
  • recurrence after year 1
A
  • genital
  • 7% seropositive
  • 90% recurrence
  • variable
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6
Q

4 stages of HSV

A
  1. painful, tingling, macular, red lesion
  2. fluid filled ulcers
  3. Burst ulcers and painful
  4. gradual healing, less likely to be swabbed
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7
Q

HSV transmission

A

May be passed on through asymptomatic shedding

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8
Q

Tests for HSV

A

HSV PCR swab

Full STI screen

  • Syphilis serology
  • HIV antibody test
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9
Q

Management of HSV 2

A

Rest
Analgesia - lidocaine ointment
Saline washing
Vaseline

Systemic antivirals

Treat before results come back

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10
Q

Antivirals for HSV 2

A

Aciclovir tds for 5 days

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11
Q

Complications of HSV

A
Urinary retention 
Adhesions 
Meningism 
Emotional distress
Recurrence
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12
Q

HSV counselling

A

Recurrence rate

Contact tracing

Asymptomatic shedding

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13
Q

HSV in pregnancy

A

Recurrence - low risk to pregnancy

Primary infection in last trimester - C - section

Do not swab in 3rd trimester

Avoid UPSI in pregnancy

HSV serology considered

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14
Q

Ulcer history

A
Pain 
Bleeding 
Previous STIs 
Sexual Hx 
Travel Hx 
Features causing immunocompromisation
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15
Q

Ulcer examination

A

Genital exam

Lymph nodes

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16
Q

Syphilis course

A

Primary:
- chancre

Secondary:

  • systemically unwell
  • rash
  • alopecia

Latent

  • early latent < 2 yrs
  • late latent > 2 yrs

Tertiary

  • neurological complications
  • CVD complications
17
Q

Chancre

A

Painless indurated ulcer

18
Q

When is syphilis infectious

A

Primary stage
Secondary Stage
Early latent phase

19
Q

Diagnosis of syphilis

A

Microscopy
Treponemal PCR swab

Blood tests:

  • Treponemal enzyme essay
  • Treponema pallidum particle agglutination assay (TPPA)
  • Rapid plasma reagin test (RPR)
  • Full STI screening including HIV
20
Q

Syphilis treatment

A

IM benzylpenicillin

Early latent - 1 dose

Late latent - 3 doses, 1 per week

21
Q

Risk factors for syphilis

A

Anal sex
MSM
Unprotected sex
Multiple sexual partners