genital symptoms Flashcards

1
Q

examples of genital symptoms

A
discharge 
pain
rashes
lumps and swellings
cuts, sores, ulcers
itching 
change in appearance 
something not right
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2
Q

causes of genital symptoms

A

STI - public and individual health problem, treatable, not always curable
other microbial - individual health problem, treatable if needed, usually curable
non-microbial - individual health issue, huge variety

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3
Q

how to determine what is an STI

A

spectrum of organisms from only transmitted by sexual contact to only transmitted by non-sexual means
large spectrum and many are both
subjective assessment when determining main transmission mode

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4
Q

in terms of microbial infection what can cause the symptoms

A

infecting organism itself
host response to organism
again a spectrum, likely a bit of both

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5
Q

examples of microbial conditions not regarded as STDs in UK

A
vulvovaginal candidosis 
bacterial vaginosis 
balanoposthitis - anaerobic/candidal
tinea cruris 
erythrasma
infected sebaceous glands
impetigo
folliculitis
cellulitis 
many more
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6
Q

vulvovaginal candidosis - causative organism

A

~70% just candida albicans
30% other - e.g. C. glabrata or mixed populations

usually acquired from bowel

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7
Q

symptoms of vulvovaginal candidosis

A

often asymptomatic carriage - change in host environment triggers pathogenicity
symptomatic = thrush - itch, discharge

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8
Q

describe the discharge in vulvovaginal candidosis

A

classically thick
cottage cheese
often just a report of increased amount

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9
Q

how common is vulvovaginal candidosis

A

very common
usually trivial
can cause a misery in minority

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10
Q

who is more likely to get vulvovaginal candidosis

A
diabetes
oral steroids
immune suppression incl HIV
pregnancy 
reproductive age group 

many cases occur in people w/o predisposing factors

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11
Q

making a diagnosis of vulvovaginal candidosis

A

characteristic hx
vaginal pH? - normal pH can be found with thrush
examination findings
investigations

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12
Q

examination findings in vulvovaginal candidosis

A

linear fissuring
erythema with satellite lesions
characteristic discharge

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13
Q

investigations for vulvovaginal candidosis

A

gram stained preparation
culture
PCR

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14
Q

gram stain for vulvovaginal candidosis

A

low sensitivity

might look at an unrepresentative patch

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15
Q

culture for vulvovaginal candidosis

A

e.g. Sabouraud’s medium
higher sensitivity but labour intensive
low specificity to determine cause of symptoms - yeast are commensal organisms so may not be the cause but still present

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16
Q

PCR for vulvovaginal candidosis

A

highest sensitivity

lowest specificity - even more likely to find ‘innocent bystanders’

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17
Q

treatment for vulvovaginal candidosis

A

often self corrects if mild

azole antifungals - clotrimazole 500mg PV once (plus clotrimazole HC if vulvitis), fluconazole 150mg PO once

resistant case - determine species and sensitivities and treat accordingly

other management - maintain skin, avoid irritants, treat dermatitis

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18
Q

how many episodes of thrush p/a is classed as recurrent

A

4 p/a

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19
Q

what is the commonest cause of abnormal vaginal discharge

A

bacterial vaginosis

10-40% of women at any time

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20
Q

symptoms of bacterial vaginosis

A

asymptomatic in 50%
watery grey/yellow ‘fishy’ discharge
may be worse after period/sex
sometimes sore/itch from dampness

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21
Q

what type of problem is bacterial vaginosis

A

biofilm problem - like dental caries; makes management difficult in some women
imbalance of bacteria
only becomes an issue when symptomatic
increased Gardnerella vaginalis, Enterococcus faecalis and Actinomyces neuii
reduced lactobacilli

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22
Q

cycle in bacterial vaginosis

A

reduction of lactobacilli, reduction in H2O2 production
raised pH
overgrowth of BV associated bacteria

23
Q

complications from bacterial vaginosis

A

usually asymptomatic/very mild symptoms

minority of women:
associated with endometritis if uterine instrumentation/delivery
associated with premature labour
increases risk of HIV acquisition

24
Q

diagnosis of bacterial vaginosis

A

characteristic hx
examination findings - thin, homogenous discharge
pH - can be more alkaline than normal
gram stained smear of vaginal discharge

25
Q

bacterial vaginosis treatment

A

abx:
- metronidazole (oral - avoid ethanol; vaginal gel)
- clindamycin (vaginal)

probiotics - replacement of lactobacilli (vaginal/oral)
vaginal acidification - maintain pH at 4.5 w/ acidifying gel

26
Q

causative organisms of balanitis and posthitis etc

A

candidal balanitis
Zoon’s balanitis (aka plasma cell balanitis)
- rash on the end of the penis
- mostly seen in uncircumcised men

27
Q

causes of Zoon’s balanitis

A

chronic inflammation 2y to overgrowth of commensal organisms plus ‘foreskin malfunction’

28
Q

causative organisms of impetigo

A

staph aureus

strep pyogenes

29
Q

causative organism of erysipelas

A

strep pyogenes

30
Q

causative organism of dermatophyte infection

A

e.g. tricophyton rubrum

psoriasis as differential dx

31
Q

causes of tinea cruris

A

dermatophytes - ‘athlete’s groin’

hygiene - important to maintain dry area to prevent growth of harmful organisms

32
Q

causative organism of erythrasma

A

corynebacterium minutissimum

33
Q

subcategories of non-microbial genital conditions

A

percieved problem only - normal findings, no clinical findings, only findings are psychological
‘real problems’ - dermatoses, structural abnormalities (congenital, acquired)

34
Q

examples of perception of abnormality but no clinical findings

A
vaginal discharge 
urethral discharge 
dysuria
genital/pelvic discomfort 
rashes
skin lumps 
penis size, scrotal lumps, labial shape

many problems are temporary, some are more persistent can lead to body dysmorphia

35
Q

lines of questioning if nil found on examination or tests results

A
regretted sexual encounter
problems in life
co-existing mental ill health - anxiety 
when did they notice the problem 
when were things last normal - family illness, friend will illness, media story
36
Q

management approach for perception of abnormality but no clinical findings

A

acknowledge the perception
what do they think is the cause - allows some conditions to be specifically covered and ruled out e.g. cancer, infertility, STD
variants of reassurance - provide alternative, benign explanation
discuss limitations of medical approach

37
Q

examples of physiological clinical signs which can be mistaken for STDs

A

Fox-Fordyce spots
vulval paillomatosis
Coronal papillae
Tyson’s glands

38
Q

what are Fox-Fordyce spots

A

sebaceous glands of the skin
more prominent in some men than others
completely normal

39
Q

what are vulval paillomatosis

A

soft projections

sometimes mistakenly treated as warts

40
Q

what are coronal papillae

A

penile pearly papules
normal features, more prominent in some than others
can be mistaken for warts

41
Q

what are Tyson’s glands

A

smooth, small vestigial glands
either side of the frenulum
usually symmetrical
can be mistaken for warts

42
Q

other causes of genital symptoms i.e. non-microbial but there is something going on

A
pain syndromes ('dynias')
dermatoses
congenital 
traumatic/iatrogenic
neoplastic
neuromuscular
manifestations of systemic disease
idiopathic 
etc.
43
Q

examples of pain syndromes

A

vestibulodynia
vulvodynia
chronic pelvic pain syndrome

44
Q

what is vestibulodynia

A

provoked introital tenderness

e.g. during penetrative sex, tampon insertion

45
Q

what is vulvodynia

A

persistent burning or aching

46
Q

what is chronic pelvic pain syndrome

A

sometimes labelled as prostatitis (but usually no ‘itis)
cause unclear
muscular dysfunction implicated in many cases

47
Q

what is a lymphocele

A

blocked lymph duct
becomes engorged with lymph
can occur as a result of increased friction, 2y to infection
can settle spontaneously - avoid friction

48
Q

what are congenital cysts

A

form during development in the uterus
can be external or internal
often don’t cause an issue

49
Q

what is an ecchymosis

A

blood blister

can occur with torn frenulum - small artery that can bleed a lot

50
Q

examples of dermatoses

A

lichen sclerosus

lichen planus

51
Q

what is lichen sclerosus

A

AI disease, scarring and thinning of skin
can close off urethral meatus
also affects women, scarring around the vagina can be mistaken for FGM

52
Q

what is lichen planus

A

cause isn’t entirely clear - thought to be AI

53
Q

indications of carcinoma

A

ulcer with firm base