Genital Infections Flashcards
How are genital infections commonly transmitted?
STDs
What conditions can Neisseria gonorrhoeae cause as it ascends the genital tract?
- Acute endometriosis
- Acute Salpingitis
- Tuboovarian Abscesses
What is syphilis caused by?
Treponema pallidum
What are the stages of syphilis and the characteristically associated lesions?
- Primary - chancre
- Secondary - Condylomata lata
- Tertiary - Cardiovascular and Nervous System
What is the histological hallmark of syphilis?
Dense inflammatory infiltrate with lymphocytes and plasma cells/Spirochetes ID’ed with silver impregnation stains
What bug causes granuloma inguinale?
Calymmatobacterium granulomatis
What is the histological finding of granuloma inguinale?
Donovan bodies
What is chancroid caused by?
Haemophilus ducreyi
What is gardnerella caused by? What is pathognomonic for the disease?
Gardnerella vaginalis; Clue cells - squamous cells covered by coccobacilli
What bug causes Chlamydia?
Chlamydia trachomatis
What morphology is seen in uscopy of Chlamydia infection?
Perinuclear intracytoplasmic inclusions with distinct borders and intracytoplasmic coccoid bodies
What is Lymphogranuloma Venereum caused by?
Chlamydia trachomatis serotypes L1 thru L3
What are the typical lesions of a person with HPV?
Verrucae and condylomata
What serotypes of HPV account for over 80% of visible condylomata?
Serotypes 6 to 11
What type of lesion does HPV cause?
Condylomata Acuminatum
HPV is shown. What are the characteristic lesions?
Koilocytes - epithelial cells with a perinuclear halo and wrinkled nucleus containing HPV particles
What is the typical bug that causes genital herpes?
HSV2
What are the typical histo characteristics of molluscum contagiosum?
Molluscum bodies - Large cytoplasmic viral inclusions
What bug causes trichomoniasis?
Trichomoniasis vaginalis
What is pelvic inflammatory disease?
PID is infection of pelvic organs due to extension of any of a variety of uorganisms beyond the uterine corpus
What are the typical culprits of PID?
N. gonorrhoeae and C. trachomatis
What are complications of PID?
- Rupture of tuboovarian abscess
- Infertility from scarring
- Increased rate of ectopic pregnancy
- Intestial obstruction from fibrous bands
What generally is the initial lesion of genital tuberculosis?
Tuberculous salpingitis
What are late sequelae of tuberculous salpingitis?
Pyosalpinx and hydrosalpinx
What is the typical presentation of Candidiasis?
Vulvar itch and white discharge
What bug causes sulfur granules and is associated with IUD use?
Actinomyces israelii
What is toxic shock syndrome caused by?
S. aureus that release the exotoxin toxic shock syndrome toxin-1 which inhibits the ability of mononuclear phagocytes to clear other toxins
