genetics- not finised Flashcards
chromosome structure
chromatids are made from ___ and are the site of ___
repetitive sequences of DNA- satellite DNA
kinetochore- attatches chromatids to spindle
heterochromatin is made of
silenced genes- condensed structure
euchromatin is made from
active genes- open structure- where transcribed genes are
chromatin structure
DNA packed with histones into nucleosomes
histones have positive charge and DNA have negative
characteristics of autosomal dominant inheritance
each child has a 50% chance of inheriting
no skipped generations
equally transmitted to females and males
male to male transmission
characteristics of sex linked inheritance
only males affected usually
can skip generations
unaffected women and men can transmit
no male to male transmission
is sickle cell recessive or dominant
recessive- both parents must be carriers
is CF recessive or dominant
recessive- needs both parents to be carriers
child’s chances of illness in recessive conditions when both parents are carriers
1 in 4
childs chances of carrying with one parent is a carrier in a recessive condition
2 in 4
huntingtins dominant or recessive
dominant
how is Duchenne’s spread
X linked inheritance
how are sex genes inherited
females get X from dad and X from mum
males get X from mum and Y from dad
X linked inheritance: mother carrier chances
50% chance each son will have
50%chance each daughter
both get an X from mother
