antibiotics- not finished

Question 1

3 main ways antibiotics work

Answer 1

inhibition of:

cell wall synthesis
protein synthesis
nucleic acid synthesis

Question 2

M.B.C

Answer 2

Minimal Bactericidal Concentration- minimum conc needed to kill the organism

Question 3

MIC

Answer 3

Minimum Inhibitory Concentration- minimum conc needed to stop growth

Question 4

antibiotics that stop cell wall synthesis

Answer 4

penicillins and cephalosporins (beta lactams)
glycopeptides

both are bacteriocidal

Question 5

cell wall synthesis: penicillin’s and beta lactams

are effective on _____

and disrupt ___

Answer 5

gram positive bacteria

peptoglycan synthesis

Question 6

cell wall synthesis: glycopeptides

are effective on

and disrupt

Answer 6

bactericidal

gram positive

assembly of peptidoglycan precursor

Question 7

cell wall synthesis: glycopeptides

route of administration

example drugs

Answer 7

parentally only- not absorbed in GI

vancomycin, teicoplanin

Question 8

antibiotics that inhibit protein synthesis:

Answer 8

aminoglycosides

macrolides

tetracyclines

oxazolidinones

cyclic lipopeptide

Question 9

inhibition or protein synthesis: aminoglycosides

are effective on ___

by interfering with

Answer 9

conc dependant bactericidal

gram negative - e.g coliform

ribosome codon reading

Question 10

inhibition or protein synthesis: aminoglycoside example

Answer 10

gentamicin

Question 11

inhibition or protein synthesis: macrolides

effective on___

by inhibiting___

Answer 11

bactericidal and static

gram positive

ribosomal translation

Question 12

inhibition or protein synthesis: macrolide example and common use

Answer 12

erythromycin- used in patients with penicillin sensitivity

Question 13

antibiotics that inhibit nucleic acid synthesis

Answer 13

trimethoprim

sulfamethoxazole

ciprofloxacin

levofloxacin