genetics - general Flashcards

general info on DNA, anatomy of genes

1
Q

what is dna

A

material that comes from hereditary info

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

what are nucleotides made of

A

-PO4
- deoxyribose sugar
- N-base (A,C,T,G)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

what holds the sugar-phosphate backbone together

A

phosphodiester bonds

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

what holds sugars and bases together

A

glyosidic bonds

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

what are the key characteristics of DNA

A
  1. double helix structure
  2. anti parallel
  3. complimentary
  4. new dna from 5’ to 3’
  5. a fork is half a bubble
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

what fn group is found at the end of the 5’ end? 3’ end?

A

phosphate -5’
hydroxyl - 3’

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

which base is unique to dna

A

thymine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

what are the differences between dna and rna

A

dna: deoxyribose, thymine, large, double stranded
rna: ribose, uracil, small, single stranded

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

purines

A

adenine and guanine
- double ring

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

pyrimidines

A

thymine and cytosine
- single ring

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

genome

A

SUM of all organisms DNA

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

histone

A

proteins that organize dna into tightly coiled structures (chromosomes)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

centromere

A

where spindle fibers attach to (non coding)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

telomere

A

end reigons of DNA, nonsense reigon that buffers loss (non coding)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

pseudogenes

A

never expressed due to mutations

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

transposons

A

jumping genes that move around genome by copying, cutting and pasting themselves into chromosomes

17
Q

endogenous retroviruses (ERV)

A

extinct retroviruses that are stuck in genome

18
Q

gene

A

specific seq or dna that codes of rna or proteins

19
Q

promoter

A

where dna transcription begins

20
Q

exons (non coding)

A

expressed into a.a

21
Q

introns (non coding)

A

removed by spliceosomes before rna goes onto being transcribed

22
Q

stop codon

A

tells ribosome where protein-coding reigon ends during dna translation
- 3 stop codons

23
Q

what happens if telomere erodes

A

cell malfunctions and dies