Genetics/ DNA Flashcards
DNA
has 4 nucleotides
- Thymine (T)
- Cytosine (C)
- Adenine (A)
- Guanine (G)
- -They all have a phosphate group and a 5 carbon sugar. They differ in their bases.
DNA Structure
- the nucleotides are put together by their common elements. The phosphate group to the 5 carbon sugar.
- the sugar phosphate back bone is strung together with the different bases sticking out to the side.
DNA Double Helix Structure
- It is read 3 prime to 5 prime
- 2 strands of DNA are connected via the different bases with hydrogen bonds
- -they are attached anti-parallel
- the same bases are always together
- the strands are duplicates of each other if read 3 prime to 5 prime on each strand
What nucleotides go together?
Adenine and Thymine A-T
Cytosine and Guanine C-G
How do you read the code of DNA?
- Take the sequence of nucleotides to give the sequence and order of the Amino acids
- Read every three bases
Codons
three nucleotides put together
-some repeat meaning they will code for the same amino acid
Chromosomes
Condensed DNA
- the DNA strands are coiled in on itself
- -they coil up together and then coil again getting shorter and more bunched or condensed into the chromosome
Histone Protein
They help condense DNA
-The DNA coils around them and they help the DNA coil together
1 double stranded helix is?
one unduplicated chromosome
2 Double stranded helix’s that are exact copies of each other become?
A duplicated Chromosome or a Chromatid and its sister Chromatid
Centromere
Where 2 chromatids attach
Kineticore
is the protein that attaches 2 chromatids at the centromere
Genes
are a discrete unit of information on a chromosome
-they code for a particular protein or trait
The first codons is?
The start Codon
Codons between genes are?
Garbage Codons that don’t make anything
Allele
different form or version of a gene
- different alleles make different traits or proteins.
- same proteins different order that changes things
Human Genome
The collection of Human Genetic code
- 46 Chromosomes
- -23 pairs
- –22 homologous/ autosomal
- –1 pair sex chromosomes
- On every homologous chromosome you have the same genes in the same place but you could have different alleles.
- you have two copies of every gene, but there can be many different alleles for the two genes
what cell in your body does not have 46 chromosomes?
Your sex cells
were do you get you traits from?
One from your mother and one from your father
Expression of Alleles
What you are going to get/see
Wild type Alleles
Just more common alleles
Mutant type Alleles
Less common Alleles
Dominance
- dominant/recessive
- Homozygous Dominant
- Heterozygous
- Homozygous Recessive
Homozygous Dominant
you will display the dominant gene
Heterozygous
you will display the dominant gene
Homozygous Recessive
is the only way you get a recessive gene
Genotype
showing/telling/saying what alleles someone has
Phenotype
what is actually expressed in the genotype
Sex Determination
- we all have to have an X chromosome it has nothing to do with sex. It has important genes that we need
- The Y chromosome is called the male chromosome. It is the male determining gene.
- If female XX
- If male XY