Genetics and Evolution Flashcards
What are chromosomes composed of
DNA and protein
Griffith experiment
used two strains of S. pneumonie to show that there was a transforming factor.
Heat killed S + live R strains killed the mice, meaning that the cell extract of the dead S conferred virulence to the R strain.
Avery, MacLeod, McCarty,
Destroyed DNA and saw that the virulence wasn’t conferred to R, showing that DNA is the molecule of inheritance.
Hershey and Chase
used two phage cultures, one labeled with P and one labeled with S, to confirm what Avery, MacLeod, and McCarty found.
gene
fundamental unit of inheritance
homologous chromosomes
two nonidentical copies of a chromosome from a mother and a father
alleles
different versions of a gene
genotype/phenotype
DNA sequence a person carries/ the physical expression of genotype
dominant/recessive
dominant - allele that is expressed no matter what other allele is
recessive - allele that is silent unless present in homozygous state
What does meiosis do?
Reduces number of copies of each chromosome from two to one, producing gametes
males - occurs in testes with haploid spermatozoa
females - in ovaries it produces ova
difference between meiosis and mitosis
meiosis has two rounds and recombination/crossing over occurs between homologous chromosomes
synapsis
when homologous chromosomes pair with each other during prophase I
synaptonemal complex
mediates synapsis
metaphase I
tetrads are aligned at the center of the cell
anaphase I
homologous chromosomes separate and sister chromatids remain together
telophase I
cell divides into two haploid cells with a single set of chromosomes