Genetics Flashcards
DNA is copied into RNA
Transcription
RNA is used to synthesize encoded protein
Translation
Central dogma
DNA –> RNA –> protein
How many H bonds between adenine and thymine?
Two
How many H bonds between cytosine and guanine?
Three
Enzyme that unzips DNA helix
Helicase
Enzyme that synthesizes short regions of RNA called primers
Primases
Which direction does DNA polymerases synthesize?
5’ to 3’ (+ strand)
Enzyme that forms covalent bonds between adjacent nucleotides
Ligase
What is the correct order of DNA replication?
Helicase, primase, DNA polymerase, DNA ligase
Temporary copy of genetic information
mRNA
Codon = how many nucleotides?
Three
Start codon
AUG
1 incorrect nucleotide
Base substitution
Mutation that codes for same amino acid as original
Synonymous/silent
Mutation that creates codon for different amino acid
Missense
Creates a stop codon
Nonsense
Addition or deletion of one or two pairs
Frameshift mutation
‘Naked’ DNA uptake by competent bacteria
Transformation
Virally mediated (phage)
Transduction