Genetic Prediction Flashcards

1
Q

Define heritability

A

The extent of differences observed in animal performance are due to variation in genetics.

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2
Q

What is the equation for EBV using b?

A

EBV = b x (phenotypic variation) OR b x (Pi - Pu)

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3
Q

Define mass selection

A

Based on ranking the animals on their own performance

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4
Q

When does h^2 = b?

A

When calculating EBV for an individual with only its own performance

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5
Q

Define animal model

A

Represents a method that makes use of phenotypic information of relatives to estimate the BV of an animal

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6
Q

Define Selection Index

A

A linear combination of phenotypic information and weighing factors that is used for genetic prediction when performance data comes from genetically similar contemporary groups

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7
Q

Define Selection Index in a simple way

A

A method of genetic prediction to combine multiple traits in an economically optimal way

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8
Q

What is selection index good with?

A

Good for within herds or flocks

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9
Q

What is a downside of selection index?

A

Phenotypes must be from genetically similar groups from the same environments

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10
Q

What does BLUP stand for?

A

Best Linear Unbiased Prediction

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11
Q

Who invented BLUP?

A

Charles R. Henderson

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12
Q

What commonly used tool in the animal industry uses BLUP?

A

EPDs

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13
Q

Define BLUP.

A

A method of genetic prediction that is particularly appropriate when performance data comes from genetically diverse contemporary groups.

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14
Q

Define BLUP simply

A

Simultaneous equations to solve for breeding value predictions

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15
Q

The higher the heritability and number of progenies, the _______________ the b.

A

higher

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16
Q

What is the equation for EBV with EPD?

A

EBV = 2xEPD

17
Q

What are the three Basis of Selection

A
  • Individual
  • Between families
  • Within families
18
Q

Define EPD

A

The expected difference between the average performance of an individual’s progeny and the average performance of ALL progeny.

19
Q

Define maternal EPDs vs Direct EPDs

A

How daughters of a sire are expected to perform compared to other breeding females.

20
Q

Define Genomic Selection

A

Use of genomic-wide genetic markers to predict the BV of selection candidates.

21
Q

What does SNP stand for?

A

Single Nucleotide Polymorphism

22
Q

How is a SNP different from a mutation.

A

The presence of an SNP is >1% present in the population.

23
Q

Define genetic marker.

A

A DNA sequence with a known physical location on a chromosome. These can help link a trait with a responsible gene.

24
Q

Are GE-EPDs used differently than normal EPDs?

A

NO!

25
Q

What are some benefits of using GE-EPDs?

A
  • reduce generation interval
  • improve accuracy