Genetic Mutations Flashcards

1
Q

mutagen

A

causes mutations

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2
Q

Silent Mutation

A

(point mutation) one nucleotide is swapped for another (wobble)(not a big deal)(usually occurs in third base)

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3
Q

Missense Mutation

A

(point mutation in 1st or second place)(new amino is synthesized, but pattern is not messed up)(can cause problems)(can affect protein folding)

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4
Q

Nonsense Mutation

A

Codes for an inappropriate stop codon (severely alters protein function/ and or stops it)(nonsense-nothing there)

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5
Q

Frameshift mutations

A

Biggest problem (cause everything to change)(messes up whole chain)(usually deletion or insertion of nucleotide instead of REPLACEMENT)

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6
Q

Chromosomal Mutations…

A

Deletion, duplication, inversion (all have literal meaning) Occurs during mitosis
(can also occur between two chromosomes; insertion and translocation)

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7
Q

Advantageous Mutations

A

Have benefit or advantage

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8
Q

deleterious mutations

A

detrimental mutations

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9
Q

loss-of-function mutations

A

can’t function normally

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10
Q

gain of function mutations

A

can be good or bad

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