Genetic Materials: DNA and RNA Flashcards

1
Q

He Isolated nuclein in WHITE BLOOD CELL nuclei.

A

Friedrich Miescher, 1869

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2
Q

He Transferred the KILLING ABILITY between TYPES OF BACTERIA.

A

Frederick Griffith, 1928

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3
Q

They Discovered that DNA TRANSMITS KILLING ability in BACTERIA.

A

Oswald Avery, Colin MacLeod, and Maclyn McCarty, 1940s

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4
Q

They Determined that the part of a VIRUS that INFECTS and REPLICATES is its nucleic acid and not its protein.

A

Alfred Hershey and Martha Chase, 1950

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5
Q

They Discovered DNA COMPONENTS, PROPORTIONS, and POSITIONS.

A

Phoebus Levene, Erwin Chargaff, Maurice Wilkins, and Rosalind Franklin, 1909 - 1950s

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6
Q

Elucidated DNA’s THREE-DIMENSIONAL STRUCTURE.

A

James Watson and Francis Crick, 1953

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7
Q

Had his GENOME SEQUENCED

A

James Watson, 2008

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8
Q

ONE or MORE LONG CHAINS of AMINO ACIDS that a protein consists of; a series of peptides.

A

Polypeptides

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9
Q

A SHORTER CHAINS of AMINO ACIDS.

A

Peptides

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10
Q

What is a SINGLE BLOCK of DNA?

A

Nucleotide

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11
Q

What is the NUCLEOBASE of PURINE?

A

Adenosine (A) and Guanine (G)

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12
Q

What is the NUCLEOBASE of PYRIMIDINE?

A

Cytosine (C), Thymine (T), and Uracil (U)

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13
Q

Nitrogenous bases which have a TWO-RINGS structure.

A

Purine

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14
Q

Nitrogenous bases which have a SINGLE-RINGS structure.

A

Pyrimidine

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15
Q

The opposing orientation of the TWO NUCLEOTIDE CHAINS in a DNA molecule is called?

A

Antiparallelism

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16
Q

On a smaller scale, the DNA COILS around
proteins called?

A

Histones

17
Q

A DNA “BEAD” is called?

A

Nucleosome

18
Q

It is usually DOUBLE-STRANDED, with DEOXIRIBOSE as the sugar, and THYMINE as a base.

A

DNA

19
Q

It is usually SINGLE-STRANDED, with RIBOSE as the sugar, and URACIL as a base.

A

RNA

20
Q

It is also known as “COLORED MATERIALS”, the chromosome substance is called?

A

Chromatin

21
Q

It is an INFORMATION-CONTAINING part of DNA because they FORM SEQUENCE.

A

Nitrogenous Base

22
Q

It is specific to PURINE-PYRIMIDINE couples.

A

Complementary Base Pairs

23
Q

How many HYDROGEN BONDS join together in A and T?

A

2 Hydrogen Bonds

24
Q

How many HYDROGEN BONDS join together in G and C?

A

3 Hydrogen Bonds

25
Q

It is the combination of MULTIPLE NUCLEOTIDES attached by strong attachments called PHOSPHODIESTER BONDS between the deoxyribose sugars and the phosphates. This creates a continuous SUGAR-PHOSPHATE BACKBONE.

A

Polynucleotide Chains

26
Q

It is form FRAMEWORKS that guides DNA STRAND.

A

Scaffold Proteins

27
Q

Each new DNA DOUBLE HELIX CONSERVES half of the original.

A

Semiconservatice

28
Q

It is an UNWINDING PROTEIN that breaks the hydrogen bonds that connect a base pair.

A

Helicase

29
Q

It HOLDS the TWO SINGLE STRANDS apart.

A

Binding Proteins

30
Q

It JOINS OKAZAKI FRAGMENTS and seals other nicks in the sugar-phosphate backbone.

A

Ligase

31
Q

A BIOTECHNOLOGY that researchers USE when REPLICATING DNA is conducted outside cells.

A

DNA Amplification

32
Q

It is the first and best-known DNA AMPLIFICATION TECHNIQUE. It uses DNA polymerase to rapidly replicate a specific DNA sequence in a test tube.

A

Polymerase Chain Reaction (PCR)