Chromosome and Karyotyping Flashcards

1
Q

It is a process of FINDING A CHROMOSOMAL
characteristics of a cell and it refers to the ANALYSIS OF CHROMOSOME.

A

Karyotyping

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2
Q

The STUDY of WHOLE SETS OF CHROMOSOMES.

A

Karyology

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3
Q

The CHROMOSOMES are depicted in a STANDARD FORMAT.

A

Ideogram or Karyogram

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4
Q

It is a type of CHROMOSOME if the CENTROMERE DIVIDES it into TWO ARMS of approximately equal length.

A

Metacentric

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5
Q

It is a type of CHROMOSOME if the CENTROMERE establishes ONE LONG ARM
and ONE SHORT ARM.

A

Submetacentric

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6
Q

It is a type of CHROMOSOME if the CENTROMERE if it PINCHED OFF ONLY a small amount of MATERIALS TOWARD ONE END.

A

Arcocentric

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7
Q

It is the MOST WIDELY USED routine banding method. The prepared and “AGED” slides are treated with the enzyme trypsin and then stained with Giemsa.

A

G-Banding (Giemsa Banding)

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8
Q

A FLUORESCENT TECHNIQUE was the FIRST BANDING METHOD developed for human chromosomes.

A

Q-Banding (Quinacrine Banding)

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9
Q

The OPPOSITE or REVERSE of the G-BANDING PATTERN. It is a USEFUL TECHNIQUE for the evaluation of euchromatic terminal ends/telomeres that are difficult to visualize with standard G-band techniques.

A

R-Banding (Reverse Banding)

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10
Q

It is useful for determining the presence of DICENTRIC and PSEUDO DICENTRIC CHROMOSOMES, and for studying marker chromosomes and polymorphic variants.

A

C-Banding (Constitutive Heterochromatin Banding)

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11
Q

C-Banding formed by the DNA is selectively depurination and denatured by?

A

Barium Hydroxide

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12
Q

The Chrosome that are present under the C-Banding are?

A
  1. Chromosome 1
  2. Chromosome 9
  3. Chromosome 16
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13
Q

A HARSHER TREATMENT of the chromosomes diminishes staining except at the HEAT-RESISTANT TELOMERES.

A

T-Banding (Telomere Banding)

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14
Q

What is USED TO STAIN THE REGIONS that contain GENES FOR RIBOSOMAL RNA?

A

Silver Nitrate

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15
Q

New techniques using FLUORESCENT DYES generate unique patterns for each chromosome.

A

Chromosome Painting

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16
Q

It is the range from SINGLE-BASE changes to ENTIRE EXTRA SET OF CHROMOSOMES.

A

Mutation

17
Q

It is a DARK COLORED; which consists mostly of highly repetitive DNA sequences.

A

Heterochromatin

18
Q

It is a LIGHT COLORED; has many protein-encoding sequences.

A

Euchromatin

19
Q

The chromosome tips in humans, and each telomere REPEATS THE SEQUENCE TTAGGG.

A

Telomeres

20
Q

The LARGEST CONSTRICTION of a chromosome. It is where SPINDLE FIBERS attach when the cell divides.

A

Centromeres

21
Q

It CONTACTS THE SPINDLE FIBERS, enabling the cell to divide.

A

Kinetochores

22
Q

The chromosome parts lie between PROTEIN-RICH AREAS and the TELOMERES.

A

Subtelomeres

23
Q

It introduced the ability to highlight individual genes. It can “PAINT” entire karyotypes by probing each chromosome with several different fluorescent molecules.

A

Fluorescence in situ hybridization (FISH)

24
Q

Cells MISSING a SINGLE CHROMOSOME or having an extra chromosome; “NOT GOOD SET”.

A

Aneuploid

25
Q

A normal chromosome number; “GOOD SET”.

A

Euploid

26
Q

Cells with ONE MISSING CHROMOSOME.

A

Monosomy

27
Q

The MEIOTIC ERROR that CAUSED ANUEPLOID.

A

Nondisjunction

28
Q

A female with one X

A

45, X

29
Q

A male with an extra X

A

47, XXY

30
Q

A male with an extra Y

A

47, XYY

31
Q

A male missing part of the long arm
of chromosome 7

A

46, XY

32
Q

A female with trisomy 21 Down
syndrome

A

47, XX

33
Q

A male with an extra X and an extra
Y chromosome

A

48, XXYY

34
Q

The result of another MEIOTIC ERROR leads to UNBALANCE GENETIC MATERIAL.

A

Isochromosome

35
Q

A chromosome in which TWO SHORT ARMS of NON-HOMOLOGOUS CHROMOSOMES BREAK and THE LONG ARM FUSE, form ONE UNUSUAL, large chromosome.

A

Robertsoninan Translocation

36
Q

A chromosome in which TWO NON-HOMOLOGOUS CHROMOSOME EXCHANGE PARTS, conserving GENETIC BALANCE but REARRANGING GENES.

A

Reciprocal Translocation

37
Q

A chromosomal inversion in which the inverted section DOES NOT include the centromere.

A

Paracentric Inversion