genetic Flashcards
Mendel’s breeding system
P generation: true breeders (homozygous, one dominant and one recessive)
F1 generation, then cross F1 with itself ot get F2, etc
Monohybrid crosses
Follows Mendel’s breeding, looks at 1 character
Recessive disorders
Carriers: Rr, carry the diseas but do not have the phenotype
Dihybird crosses
looks at 2 characters, true breeding parents for each character (AAbb x aaBB or AABB x aabb)
studies genres on 2 loci on non homologous chromosomes
law of independent assortment
when genes are on different chromosones, during meiosis, the allele a gamete receaves is independant of the one another gametes recessives
during metaphase, the pink can line up to the right or to the left, independently of the fact that another pink is on the right
can find the number of possibe different gamete by doing formula 2^n
n:number of heterozyngous gene
law of segregation
During the formation of gamete, each gene separates from each other so that each gamete carries only one allele for each gene.
Incomplete dominance
neither allele is dominant, the level of dominance is determined by the heterozygous or homozygous of the genes (ex: red, pink, white)
Codominance
each allele does for a slightly different protein, but both alleles are visible on the same phenotype ex: blood bype, AB
peliotropy
1 genre has multiple phenotypic effect, affects many characters
epistasis
effect of one gene is modifiend by one or several other genes ex: a gene masks the expression of another
polygenic
multiple independent pairs of gene have additive, so a range of phenotype alont a continuum
genes on sex chromosomes
sex chromosomes containt major sex-determining genes, y chromosome determines male sex,
X/Y linked: only on x/y part of chromosome, no independent assortment
females are often carriers or recessive genes, males are more likely to have abnormal phenotypes because of the lack of dominant back up
x-inactivation
to compenseate in double dose x chromosome gene, mammals female have 1 x that is mostly inactive in somatic cells, the other inactive will be called a barr body, random and permanent in somatic cells
inactivation is not complete, genes in homologous region are expressed,
genes and environment
genes set the limit for the phenotype, environment molds the phenotype within its limits