General Surgery Flashcards
List 5 indications for splenectomy
Traumatic splenic rupture Anatomic defects Severe transfusion dependent hemolytic anemia Refractory immune cytopenias Metabolic storage diseases Secondary hypersplenism
List 4 risk factors for pyloric stenosis
-Family history PS
Neonate erythromycin use in 1st 2 weeks of life
-First born
-Male
-Conditions-Apert, Zellweger, T18, eosinophilic gastroenteritis, Smith lemli opitz
What is the typical age of presentation of pyloric stenosis?
2 weeks – 2 months
Prematures diagnosed later
List 4 clinical features of pyloric stenosis
Projectile vomiting
Hungry in between
Visible gastric perstaltic wave
Olive (above and to right of umbilicus)
List the ultrasonographic diagnostic criteria for pyloric stenosis?
- Pyloric thickness >=4 mm
2. Pyloric length >=14 mm
Why do you need to correct alkalosis prior to pyloromyotomy?
Prevent post-op apnea
What fluid should you use for patient with pyloric stenosis and hypokalemic, hypochloremic metabolic alkalosis AND WHY?
Give large amounts of chlorinatedfluid=D5W0.45NS +20mmol/L of KCl
A) Chloride will help decrease the bicarb (incr Cl in IVF more strongly correlated with decr in serum HCO3)
B) Solution should correct hyponatremia and hypokalemia as well
C) Want to treat alkalosis prior to surgery to prevent apnea
What is the most common age of presentation of intussuseption?
3 months – 3 years
90% <2 years
In a child with intususseption, above what age should you think about a pathologic lead point?
> 2 years
List 5 pathologic lead points in intususseption
Meckel’s diverticulum (most common) Polyps Intestinal duplication Neurofibroma Henoch-Schonlein purpura Appendix Hemangioma Foreign body Ectopic mucosa Hamartoma Peutz-Jaeger’s*** Malignancy (lymphoma, SB tumors, melanoma) CF
List 3 contraindications to air enema in intususseption
Peritonitis
Persistent hypotension
Free air/pneumoperitoneum
List 3 conditions associated with malrotation
CDH
Gastroschisis
Omphalocele
Heterotaxy syndrome (CHD, malrotation,and asplenia or polysplenia)
List 3 conditions causing bilious vomiting
- Midgut volvulus
- Malrotation
- Duodenal or other atresias
- Hirschsprung’s disease
- Ileus
List 3 conditions associated with duodenal atresia
Trisomy 21 Malrotation Congenital heart disease GU anomalies
Why should you do hearing test in hirschsprungs?
Associated with Waardenburg syndrome
Which is more likely to be associated with other congenital anomalies-omphalocele or gastroschisis?
Omphalocele-80% associated with anomalies
List 3 conditions associated with omphalocele
Beckwith Wiedmann***most common
CHARGE
OEIS (Omphalocele-exstrophy-imperforate anus-spinal defects)
Pentalogy of Canrell ( defects involving the diaphragm, abdominal wall, pericardium, heart and lower sternum.)
Aneuploidy (trisomies 13>18> 21)
List 3 anomalies associated with gastroschisis
Most cases have no extraintestinal abnormalities
Associated GI problems are common:
- Intestinal atresia
- Malrotation
- Stenosis
List 2 steps in the initial management of abdominal wall defects
- NG tube to decompress the stomach
- Wrap bowel in saline soaked gauze and plastic wrap
- IV access and start TFI 120 mL/kg/day (include NaCl in maintenance
solution) - Broad spectrum antibiotics
- Keep neonate in thermoneutral environment
List 3 long term complications of gastroschisis
Decreased GI motility Bowel obstruction***(most common) Perforated bowel/strictures GERD Cholestasis Short Bowel
What is the natural history of umbilical hernia?
Most appear before 6mo and resolve by 1yr
Large hernia disappear by 5-6yrs
Above what size are umbilical hernias unlikely to close spontaneously?
> 2 cm
Indications for surgery for umbilical hernia
Persists beyond 5yrs
Symptomatic
Strangulated
Progressively larger after 1-2 yrs
What is the anatomy of indirect hernia?
Most common!
Due to patent process vaginalis
When is the risk of incarceration highest for inguinal hernia?
1st year of life
List risk factors for inguinal hernias
Prematurity
Urogenital • Cryptorchidism • Exstrophy of the bladder or cloaca • Ambiguous genitalia • Hypospadius/epispadius
Increased peritoneal fluid
• Ascites
• Ventriculoperitoneal shunt
• Peritoneal dialysis catheter
Increased intra-abdominal pressure
• Repair of abdominal wall defects
• Severe ascites (chylous)
• Meconium peritonitis
Chronic respiratory disease
• Cystic fibrosis
Connective tissue disorders • Ehlers-Danlos syndrome • Hunter-Hurler syndrome • Marfan syndrome • Mucopolysaccharidosis
When should hernias be repaired?
Early repair (6-12mo) reduces risk of incarceration and complications
Urgent referral if child is <1yr
Management of incarcerated hernia
Attempt reduction
Surgical repair 24-48 hours later
Management of strangulated hernia
Surgery ASAP
Anatomy of direct inguinal hernia
Rare in children
Acquired
Groin masses that extend toward femoral vessels due to muscular defect
What is the anatomy of malrotation?
Failure of the cecum to move into the right lower quadrant which prevents normal broad based adherence to the posterior abdominal wall
The mesentery, including SMA, is tethered by narrow stalk–>prone to volvulus
Ladds bands between cecum and RUQ can compress duodenum
List 5 risk factors for gall stones
Hemolytic disorders (sickle cell, HS) Obesity Crohn's disease Short gut (esp ileal resection) CF TPN Diuretic use Cephalosporin use
List 3 conditions that have increased risk of hirschsprungs
T21 Goldberg-Shprintzen Smith-Lemli-Opitz Shah-Waardenburg Cartilage-hair hypoplasia Congenital hypoventilation syndrome
Differential for delayed passage of meconium
HD Meconium ileus Small left colon syndrome Intestinal atresia ARM
What was the risk of re-intussuseption after air enema reduction?
10%
Should be observed 12-24 hours
What serum marker is elevated antenatal in abdominal wall defects (gastroschisis and omphalocele)?
Elevated maternal serum AFP
What antenatal US finding in omphalocele is associated with aneuploidy?
80% contain part of the liver
Non-liver containing is associated with fetal aneuploidy
List 2 differences on physical exam between gastroschisis and omphalocele
- Presence of covering membrane
- Present in omphalocele - Location of defect
- Gastroschisis: right of the umbilical cord insertion site
- Omphalocele: midline - Liver location
- Gastroschisis: intracorporeal
- Omphalocele: extracorporeal
Of the following, which is most commonly associated with extraintestinal anomalies:
1) Duodenal atresia
2) Jejunal atresia
3) ileal atresia
Duodenal atresia-Most commonly T21 (33%)
List 3 congenital anomalies assocaited with duodenal atresia
CHD Malrotation Annular pancreas Renal anomalies EA Skeletal malformations ARM
Why is rectal biopsy gold standard to diagnose Hirschsprungs instead of contrast enema?
10% of Hirschsprung’s won’t have transition zone on constrast enema
During what weeks GA does intestine usually rotate during fetal development?
5th-12th week gestation
List 2 contraindications to air enema reduction in intussusception (past SAQ)
- Prolonged intussusception
- Signs of shock
- Peritonitis
- Intestinal perforation
- Pneumatosis intestinalis
List 2 situations in which air enema reduction for intussusception would be unsuccessful (past SAQ)
- Intussusception due to pathologic lead point
2. SB-SB intussusception
In what age group is appendicitis most common?
12-18 years
Rare in children <5 years
List the criteria of the Pediatric Appendicitis score
- Fever >38°C (1)
- Anorexia (1)
- Nausea/vomiting (1)
- Cough/percussion/hopping tenderness (2)
- Right lower quadrant tenderness (2)
- Migration of pain (1)
- Leukocytosis >10,000 (109/L) (1)
- Polymorphonuclear-neutrophilia >7,500 (109/L) (1)
- Score of ≤2= very low likelihood of appendicitis
- Score of ≥8 are highly associated with appendicitis
What are the ultrasound criteria for diagnosis of appendicitis?
- Wall thickness ≥6 mm
- Luminal distention
- Lack of compressibility
- Complex mass in the RLQ or a fecalith
- Normal appendix must be visualized to exclude appendicitis by ultrasound
When should patients with appendicitis have surgery?
Semi-elective
Within 24-48 hr of diagnosis
Management of perforated appendicitis
- Fluid resuscitation
- Antibiotics-Amp, gent, flagyl
- Percutaneous drainage of collections by IR
- Delayed appendectomy
List 3 complications of appendicitis
- Wound infection
- Intrabdominal abscess***most common
- Post-op ileus
Treatment of perianal abscess
In infants:
1. No treatment, even if fistula
In children:
- Large abscesses require I+D
- Limited role for antibiotics (unless systemically unwell or immunocompromised)
- Surgery if fistulas
List three conditions associated with perianal fistulas
- Repaired HD
- TB
- Crohns
List 3 initial management priorities in CDH
- Immediate intubation and sedation
- Avoid prolonged PPV
- Treat PHTN
When are most CDHs repaired?
Most centers wait at least 48 hr after stabilization and resolution of the pulmonary hypertension
List 3 long term complications of CDH
BPD GERD Delayed growth in first 2 years of life Bowel obstruction Neurocognitive defects Scoliosis
What is diaphragmatic eventration?
Abnormal elevation of the hemidiaphram, because of thinned diaphragmatic muscle
Elevated hemidiaphgram on CXR
How do you differentiate between diaphgragmatic eventration or CDH?
U/S
List 3 acute complications of G-tube insertion
- Pneumoperitoneum
- Peritonitis
- Ileus
- Perforation
How do you treat hypergranulation tissue at a G-tube site?
- Silver Nitrate Ablation
- Hypertonic saline or steroid creams
What should be done for a G-tube that is pulled out?
If mature tract (>4 weeks):
-Replace with foley
If not mature tract:
- Do not replace
- Allow tract to heal
- Replace G-tube at difference site
List 3 complications of short gut syndrome
FTT Malabsorption Micronutrient deficiency Liver disease Gall stones Increased risk of infection Hyperoxaluria and kidney stones Oral aversion