General surgery Flashcards
which cause of haematuria is most common and associated with polycythemia?
renal adenocarcinoma
which tumour causes haematuria and usually presents in the first 4 years of life?
nephroblastoma
also known as a Wilms tumour
may cause lung mets
what do raised AFP levels in association with a risk factor such as hepatitis B suggest a diagnosis of?
hepatocellular carcinoma
raised AFP + jaundice + risk factor = hepatocellular carcinoma
which cancers is CA19-9 raised in?
pancreatic cancer
cholangiocarcinoma
why should biopsy be avoided in hepatocellular carcinoma diagnosis?
it seeds tumour cells through a resection plane
1st line Ix = CT + MRI
in cases of diagnostic doubt, serial CT and aFP measurements are preferred
in males with suspected hepatocellular carcinoma and raised AFP, what other structure must be examined?
the testes
what is the main risk factor for cholangiocarcinoma?
PSC
name the tumour markers raised in cholangiocarcinoma?
CA19-9, CEA and CA 125
which disease process is associated with liver cysts
(70%), berry aneurysms (25%) and pancreatic cysts (10%)?
adult polycystic kidney disease
causes painless haematuria and renal impairment, may be a FHx of brain haemorrhage
what is the definitive diagnostic investigation for small bowel obstruction?
CT abdomen
which condition is epigastric pain that worsens on lying down and radiating to the back a typical picture of?
pancreatitis
what is the 1st line medical management of small bowel obstruction?
IV fluids, NG tube for gastric decompression and additional potassium
“drip and suck”
which class of analgesic should be avoided in patients who have just had a renal transplant?
NSAIDs
they may be nephrotoxic
where is the deep inguinal ring palpated?
why is this relevant clinically?
the mid point of the inguinal ligament
relevant clinically as it helps establish direct from indirect hernias
if you press on deep inginual ring and hernia stops protruding, it’s an indirect hernia
if it continues to protrude, its a direct hernia
the risk of transfusion related lung injury is greatest with what type of transfusion?
plasma components
compare the features of familial adenomatous polyposis (FAP) and HNPCC (Lynch syndrome)
FAP: typically over 100 colonic adenomas
HNPCC: colonic tumours likely to be right sided and mucinous with extra colonic cancers
which type of bone tumours have a radiolucent, soap bubble appearance?
giant cell tumours
they present as pain or pathological fractures and commonly metastasise to lungs
describe the biochemical features of osteomalacia?
hypocalcemia
low urinary calcium
which bone tumour is most common in 10-20 y/o males and presents as a lytic lesion with onion type periosteal reaction?
Ewings sarcoma
how would a liver haemangioma present?
a large hyper echoic lesion on US in the presence of normal AFP.
if the lesion has a raised AFP then it will almost always be a hepatocellular carcinoma
how can hydroceles be differentiated from hernias as causes of scrotal swelling?
hydroceles transilluminate
hernias dont
name 3 features seen in portal hypertension?
ascites
splenomegaly
caput medusae
which nerve is at risk of damage in a total hip replacement?
sciatic nerve
damage to it manifests as foot drop/inability to plantaflex
common peroneal and tibial nerve are branches of the sciatic
what is Fitz Curtis syndrome?
occurs in patients with pelvic inflammatory disease
the PID (usually due to chlamydia) causes formation of fine peri-hepatic adhesions which may cause ab pain
compare how congenital inguinal and umbilical hernias are managed?
inguinal: repair ASAP
umbilical: manage conservatively (most resolve by age 4-5)
which classes of shock are the only ones with hypotension?
class 3 and class 4
In class 3, patient is conscious but confused
in class 4, patient is unconscious
which skin lesion frequently occurs at the site of previous trauma?
dermatofibromas
what is the difference between an epidermoid cyst and a pilar cyst?
both have a central puncture and may contain small quantities of sebum
epidermoid cyst: the cell lining is normal epidermis
pilar cyst: the cell lining is the outer root sheath of the hair follicle
name symtoms that suggest a femoral nerve injury ?
weak hip flexion
weak knee extension
impaired quadriceps tendon reflex
sensory deficit in anteromedial aspect of thigh
what make up 90% of urothelial malignancies?
transitional cell carcinomas
may offer anywhere along the urinary tract
cause painless haematuria
in which GI ulcer is the epigastric pain relieved by eating?
duodenal ulcer
in which GI ulcer is the gastric pain exacerbated by eating?
gastric ulcer
what can an enterovesical fistula commonly occur secondary to?
colorectal malignancy
presents with bubbly urine and repeated UTIs
where is meckel’s diverticulum most commonly located?
typically 2 feet proximal to the ileocaecal valve
when may the pain be worse with meckels diverticulum?
typically worse after meals
the area of meckels diverticulum may contain ectopic gastric mucosa which may secrete acid with subsequent bleeding and ulceration
what is the curative Tx for biliary colic?
elective laparoscopic cholecystectomy
as long as there are no features suggesting acute infection
what is the most likely composition of a renal stone with a stag horn calculus?
what is the most common type of renal stone?
struvite
calcium oxalate is most common type of renal stone
what type of cancers are 90% of colorectal cancers?
adenocarcinomas
what is the best indicator of severity and can indicate prognosis in acute pancreatitis?
calcium
hypocalcemia is a poor prognostic factor
what is the most common type of renal cell cancer?
clear cell
what is Charcot’s triad?
what is it indicative of?
RUQ pain, fever and jaundice
indicates suspected ascending cholangitis
what is the most common form of prostate cancer?
adenocarcinoma
accounts for >95% of cases
what is the cause of a scrotal swelling that you cant get above?
inguinoscrotal hernia
it is the only condition where it is not possible to palpate above the swelling
what is the only testicular tumour that transilluminates?
hydrocele
where are diverticula most commonly found?
sigmoid colon
what analgesic should be given in the acute management of renal colic?
diclofenac 75mg IM
what is the surgery of choice for distal colon cancers?
a loop colostomy
how can epididymis-orchitis be differentiated from testicular torsion?
epididymis-orchitis usually causes pyrexia and a positive urine dipstick, TT does not
when is the faecal immunochemical test (FIT) indicated in colorectal cancer?
recommended for patients with new symptoms of possible colorectal cancer who do not meet the 2 week wait criteria
how are the majority of patients with ascending cholangitis managed?
ERCP within 24-48 hours
what is charcot’s triad?
what condition does it indicate?
fever, jaundice, RUQ pain
suggests ascending cholangitis
obstructive jaundice
why is laparoscopic cholecystectomy not indicated in acute ascending cholangitis?
it cannot remove bilestones in the common bile duct
it is also more risky in septic patients than ERCP
compare the reasons tamsulosin and finasteride are used in BPH?
tamsulosin: A1 antagonist- improves voiding symptoms (poor flow, hesitancy, post void dribble)
finasteride: 5 alpha reductase inhibitor - used to slow disease progression and indicated if patient has significantly enlarged prostate
what is the safest surgical procedure to do in a patient with bowel perforation?
Hartmans procedure
it can then be reversed later
what is the definition of a Hartmanns procedure?
sigmoid colectomy and formation of an end stoma
what class of drug is tolterodine?
when can it be used in BPH?
an antimuscarinic
can be used in patients with overactive bladder in BPH who have not responded to A blocker and 5- alpha reductase inhibitor