Anaesthetics Flashcards
what ASA classification is anyone who smokes?
ASA 2
so is anyone who is a social drinker, pregnant, obese (BMI 30-40), has well controlled DM
what ASA class is a patient with end stage renal disease undergoing regular scheduled dialysis?
ASA III
what ASA class would a patient be who is not expected to survive without the operation?
ASA 5
which artery is most at risk of complications during laparoscopic ports and surgical drains?
inferior epigastric artery
which nerve is most at risk of complication during an axillary node clearance?
long thoracic nerve
which nerve is most at risk during a posterior approach to the hip for replacement?
sciatic
name the 2 forms of inhaled anaesthesia?
- volatile liquid anaesthetics (isoflurane, desflurane, sevoflurane)
- nitrous oxide
which inhaled anaesthetic is used for induction of anaesthesia and which is used to maintain anaesthesia?
volatile liquid anaesthetics used to induce and maintain anaesthesia
nitrous oxide used to maintain anaesthesia only but can be used for analgesia in labour
what is probably the most commonly used induction agent for general anaesthesia?
what is it’s mechanism of action?
propofol
it potentiates GABAa
why is propofol useful in patients with a high risk of post op vomiting?
it has some anti-emetic effects
which IV anaesthetic causes less hypotension than propofol and thiopental and is therefore used more commonly in cases of haemodynamic instability?
what is one side effect of this anaesthetic?
etomidate
it can cause primary adrenal suppression
which anaesthetic is particularly useful in trauma as it doesnt cause a drop in blood pressure?
ketamine
what is the mechanism of action of ketamine?
blocks NMDA receptors
which airway adjunct has poor control against reflux of gastric contents?
laryngeal mask
name when the following drugs are stopped prior to surgery:
a) warfarin
b) LMWH
c) anti-platelet (clopidogrel)
a) warfarin - 5 days before surgery
b) heparin- 24 hours prior to surgery
c) anti-platelet - 7 days before surgery
which is the only cardiac drug that is usually stopped in the peri-operative period?
how long prior to surgery is it stopped and why?
ACEi
stopped the day before surgery
due to risk of AKI
what are high risk patients who have stopped warfarin given for the 5 interim days prior to surgery?
they are bridged with heparin
patients who are considered high risk:
- AF
- VTE within 3/12
- metal heart valve
- multiple replacement valves
when should warfarin be restarted if there is no major bleeding during procedure?
restart it on day of procedure and cover with heparin
recheck INR in 48 hours
name 2 type of GABAa agonists?
propofol
thiopental
used as induction agents
name 3 types of muscle relaxants used?
what is their mechanism of action?
rocuronium
vecuronium
suxamethonium
they are all nACh antagonists
(n stands for nicotinic)
what can be used to reverse the actions of muscle relaxants (nACh antagonists)?
neostigmine
it is an acetylecholineesterase inhibitor –> therefore it increases the amount of ACh in the synaptic cleft
what is used to manage bradycardia during GA?
atropine IV 500mcg