General Principle Flashcards

1
Q

Study of effect of drugs on the function of living systems

A

Pharmacology

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2
Q

Study the effect of ‘poison’ on the function of living system

A

Toxicology

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3
Q

Any strange substances to our body

A

Xenobiotic

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4
Q

Chemical/ Physical agent that can cause toxicity when in high doses

A

Toxic agent

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5
Q

Chemical/ Physical agent that can produce toxicity even in low doses

A

Poison

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6
Q

Toxic compound produced by biological systems

A

Toxin

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7
Q

When a compound reaches values above safe maximum dose

A

Intoxication

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8
Q

Constellation of toxic effects

A

Toxic syndrome

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9
Q

Relationship of an individual test subject or system to increasing and/ or continuous doses of a chemical

A

Graded dose response

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10
Q

Determined by the distribution of responses to increasing doses in a population of test subjects or systems

A

Quantal dose response

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11
Q

The concentration can cause 50% of tested individual to have toxic effect

A

Toxic Dose (TD50)

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12
Q

concentration necessary to inhibit 50% of measured response in an in vitro system

A

Inhibitory Concentration (IC50)

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13
Q

Antidote:

Acetaminophen

A

Acetylcysteine

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14
Q

Antidote:

Acetylcholinesterase Inhibitors

A

Atropine

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15
Q

Antidote:

Iron salts

A

Deferoxamine

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16
Q

Antidote:

Methanol, Ethylene glycol

A

Ethanol

17
Q

Antidote:

Mercury, Lead

A

Metal chelators

18
Q

Antidote:

Narcotic drugs

A

Naloxone

19
Q

Antidote:

Antumuscurinics/ cholinergics

A

Physostigmine

20
Q

Antidote:

Organophosphates

A

Pralidoxime

21
Q

An indicative of exposure, effect, susceptibility or clinical disease

A

Biomarker