Drug Abuse and action Flashcards

1
Q

The intake of chemical substances that are not used legally or as prescribed by the physician

Chronic use of any chemical substance to alter states of body or mind for other than medically warranted purposes

A

Drug abuse

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2
Q

Compulsive nature of the drug use despite physical or psychological harm to the user and society and includes both illicit and licit drugs

A

Drug addiction

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3
Q

Characterized by tolerance and withdrawal symptoms when user is abstinent

A

Drug dependence

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4
Q

Lead to severe dependence or addiction ; more dangerous with higher risk of dependence

A

Hard drugs

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5
Q

Doesn’t cause dependence but still can lead to addiction

A

Soft drugs

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6
Q

illegal drugs, cannot be prescribed

A

illicit drugs

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7
Q

Synthetic drug that is very similar in chemical makeup to an existing drug exerts similar effect

A

Designer drug

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8
Q

drugs used for non-medical purposes

A

Recreational drug

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9
Q

Drugs that have numbing/ paralysing properties

A

Narcotics

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10
Q

Drugs that speed up mental and physical processes, increase level of dopamine in brain

A

stimulants

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11
Q

Reduce arousal and stimulation

A

Depressants

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12
Q

Diverse group of drugs that alter perceotion, thoughts and feelings

A

Hallucinogens

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13
Q

Pleasureable activity

A

release of dopamine

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14
Q

Dopamine is released into a cluster of nerve cells in _____

A

nucleus accumbens

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15
Q

Drug abuse on reward system

A

massive release of dopamine

Speed, intensity and reliability of dopamine release

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16
Q

Natural alkaloid extracted from the leaves of Erythroxylon coca and processed into paste or powder form

A

Cocaine (benzoylmethylecgonine)

17
Q

Mechanisms of cocaine

A

Interferes with reuptake of monoamines, particularly dopamine (but also NA and 5HT)

stimulate dopamine secretion in dopaminergic pathways in the brain; this will cause a chronic stimulation of receptors

18
Q

Management of cocaine overdose

A

Benzodiapines

Phenobartal

Non-depolarizing neuromuscular blockers

19
Q

Mechanisms of Amphetamine and Amphetamine-like drugs

A

Increase the release of norepinephrine, dopamine, and serotonin

Inhibition of reuptake

20
Q

Source of Opiates and Opioids

A

Opium poppy

21
Q

Mechanisms of Opiates and Opioids

A

Binds to specific opioid receptorss

Activating the u-opioid and k- receptors in the CNS

Building up dopamine

22
Q

Leaves contain alkaloid mitragynin which interacts with opioid receptors

A

Kratom (Mitragyna Species)