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Pathology > General Path > Flashcards

General Path Flashcards

0
Q

At what temperature does circulatory arrest occur?

A

< 19

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1
Q

How long does acute inflammation last?

A

Up to 3 days.

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2
Q

What does hypothermia do to the oxygen dissociation curve?

A

Shifts oxygen dissociation curve to the left - so increases oxygen content of blood at a given temperature

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3
Q

What is ischaemia?

A

Abnormal reduction in blood supply to a tissue

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4
Q

What are the stages of ischaemia related cell injury?

A
  1. Decreased oxidative phosphorylation
  2. Decreased ATP synthesis
  3. Sodium/potassium channel is ATP dependent and subsequently fails
  4. The cell begins to swell as do mitochondria and endoplasmic reticulum
  5. Protein synthesis fails
  6. Membrane damage
  7. Calcium influx in to cell
  8. Cell death
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5
Q

SIRS

A
  1. Temp > 38 20 or pCO2 < 32mmHg (4.3kPa)

4. WCC >12 or 10% immature forms

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Pathology (23 decks)

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