General - Laatste dingen 4 Flashcards
Choleliths
a. calcium bilirubinate
b. calcium phosphate
c. calcium chorolaat
d. calcium bilirubinate and calcium phosphate
d. calcium bilirubinate and callcium phosphate (MOST OFTEN CALCIUM BILIRUBINATE)
Congenital stenosis more commOn in
a. semilunar valves
b. AV valves
a. semilunar valves
Aortocardiac fistula
a. left side systolic
b. left side diastolic
c. left side continous
d. right side systolic
e. right side diastolic
f. right side continuous
f. right side continuous
AF
a. absent S3
b. louder S3
c. absent S4
d. louder S4
c. absent S4
MVP murmur
a. mid-late systolic or holosystolic cresendo
b. band shaped, holosystolic or pansystolic
c. loud musical, honking, holosystolic or pansystolic
a. mid-late systolic or holosystolic cresendo
Dgenerative MV
a. mid-late systolic or holosystolic cresendo
b. band shaped, holosystolic or pansystolic
c. loud musical, honking, holosystolic or pansystolic
b. band shaped, holosystolic or pansystolic
RCT MV
a. mid-late systolic or holosystolic cresendo
b. band shaped, holosystolic or pansystolic
c. loud musical, honking, holosystolic or pansystolic
c. loud musical, honking, holosystolic or pansystolic
Digoxin
a. AF
b. Ventricular ectopy
a. AF (CONTRAINDICATED IN VENTRICULAR ECTOPY)
Enteroliths
a. calcium bilirubinate and calcium phosphate
b. ammonium magnesium phosphate (struvite)
c. calcium bilirubinate
d. calcium phosphate
b. ammonium magnesium phosphate (struvite)
Brachygnathism
a. parrot mouth
b. monkey or sow mouth
a. parrot mouth
Traction diverticula
a. dilation with broad neck
b. flask shape with small neck
a. dilation with broad neck
Prognathism
a. parrot mouth
b. monkey or sow mouth
b. monkey or sow mouth
True diverticula
a. dilation with broad neck
b. flask shape with small neck
a. dilation with broad neck
Pulsion diverticula
a. dilation with broad neck
b. flask shape with small neck
b. flask shape with small neck
False diverticula
a. dilation with broad neck
b. flask shape with small neck
b. flask shape with small neck
Risk gastric rupture
a. mare, grass hay, not feeding grain
b. mare, grass hay, grain
c. gelding, grass hay, not feeding grain
d. gelding, grass hay, grain
c. gelding, grass hay, not feeding grain
Lymphoma often
a. IgA deficiency
b. IgE deficiency
c. IgG deficiency
d. IgM deficiency
d. IgM deficiency
Increase MCV
a. regenerative anemia
b. non-regenerative anemia
a. regenerative anemia
Iron deficiency
a. low ferritin
b. high ferritin
a. low ferritin
Iron deficiency
a. low transferrin saturation
b. high transferrin saturation
a. low transferrin saturation
Iron deficiency
a. decreased total iron binding capacity (TIBC)
b. no difference in total iron binding capacity (TIBC)
c. increased total iron binding capacity (TIBC)
c. increased total iron binding capacity (TIBC)
Iron deficiency
a. decreased MCV/MCHC
b. increased MCV/MCHC
c. increased MCV, decreased MCHC
d. decreased MCV, increased MCHC
a. decreased MCV/MCHC
Iron deficiency
a. microcytosis, hyperchromic
b. macrocytosis, hyperchromic
c. microcytosis, hypochromic
d. macrocytosis, hypochromic
c. microcytosis, hypochromic
Iron deficiency
a. high transferrin
b. low transferrin
a. high transferrin
Myeloid-erytrhoid ratio <0.5 (normal: 0,5-3,76)
a. myeloid regeneration and erythrocyte suppression
b. erytrhocyte regeneration and myeloid suppression
b. erytrhocyte regeneration and myeloid suppression
Myelophthisis
a. reduction in all cellular ellements
b. presence of abnormal cells
a. reduction in all cellular ellements
Myelodysplasia
a. reduction in all cellular ellements
b. presence of abnormal cells
b. presence of abnormal cells
Hemophilia A and B
a. VII and IX
b. VIII and IX
c. VII and X
d. VIII and X
b. VIII and IX (RESPECTIVELY)
Fibrinolysis
a. plasminogen –> plasmin by tPa
b. fibrinogen –> fibrine by tPa
c. plasminogen –> plasmin by urokinase
d. fibrinogen –> fibrine by urokinase
a. plasminogen –> plasmin by tPa (BUT ALSO SOME BY UROKINASE)
Adverse reaction on blood transfusion
a. I
b. II
c. III
d. IV
a. I
Tranexamic acid
a. reversibly block lysine binding on plasminogen to prevent plasmin formation
b. irreversibly block lysine binding on plasminogen to prevent plasmin formation
c. reversibly block taurine binding on plasminogen to prevent plasmin formation
d. irreversibly block taurine binding on plasminogen to prevent plasmin formation
a. reversibly block lysine binding on plasminogen to prevent plasmin formation
Glanzmann’s thromboasthenia
a. defect platelet fibrinogen receptor > epistaxis
b. decreased fibrinogen binding in response to thrombin
c. excessive hemorrhage, marked aPTT
d. x-recessive
a. defect platelet fibrinogen receptor > epistaxis
Atypical equine thrombasthenia
a. defect platelet fibrinogen receptor > epistaxis
b. decreased fibrinogen binding in response to thrombin
c. excessive hemorrhage, marked aPTT
d. x-recessive
b. decreased fibrinogen binding in response to thrombin
vWF
a. platelet adhesion/aggregation, stabilizes factor VIII (APTT can be increased)
b. platelet adhesion/aggregation, stabilizes factor VIII (PT can be increased)
c. platelet adhesion/aggregation, stabilizes factor VII (APTT can be increased)
d. platelet adhesion/aggregation, stabilizes factor VII (PT can be increased)
a. platelet adhesion/aggregation, stabilizes factor VIII (APTT can be increased)
Prekallikrein deficiency
a. defect platelet fibrinogen receptor > epistaxis
b. decreased fibrinogen binding in response to thrombin
c. excessive hemorrhage, marked aPTT
d. x-recessive
c. excessive hemorrhage, marked aPTT (BELGIAN AND MINIATURE HORSES FAMILIES)
Hemophilia A
a. defect platelet fibrinogen receptor > epistaxis
b. decreased fibrinogen binding in response to thrombin
c. excessive hemorrhage, marked aPTT
d. x-recessive
d. x-recessive (FACTOR VIII)
Pancytopenia
a. reduced RBC
b. increased RBC
c. reduced WBC
d. reduced RBC and WBC
d. reduced RBC and WBC
Aplastic anemia
a. pancytopenia
b. reduced RBCs
c. reduced WBCs
a. pancytopenia
Polycythemia vera
a. primary absolute erythrocytosis
b. secondary erythrocytosis
a. primary absolute erythrocytosis
Primary absolute erythrocytosis
a. increase in erythropoietin
b. no increase in erythropoietin
b. no increase in erythropoietin
Secondary erythrocytosis
a. increase in erythropoietin
b. no increase in erythropoietin
a. increase in erythropoietin
Epidermis
a. basal, granular, spinous, cornified
b. granular, spinous, basal, cornified
c. basal, spinous, granular, cornified
d. granular, spinous, cornified basal
c. basal, spinous, granular, cornified
JBE-1
a. LAMC2
b. LAMC3
c. HERDA
d. Ehlers
a. LAMC2 (FRENCH AND BELGIAN DRAFTS)
JBE-2
a. LAMC2
b. LAMC3
c. HERDA
d. Ehlers
b. LAMC3 (AMERICAN SADDLEBREDS)
Equine viral papillomatosis
a. Culicoides imicola
b. Culex pipiens
c. Tabanidae (horse and deer flies)
d. Simulium spp. (black flies)
d. Simulium spp. (black flies)
Equine coital exanthema
a. EHV-2
b. EHV-3
c. EHV-4
d. EHV-7
b. EHV-3
Pastern dermatitis
a. Staphylococcus
b. D. congolensis
c. H. asini
d. Damalinia equi
b. D. congolensis
Biting lice
a. Damalinia equi
b. Haematopinus asini
a. Damalinia equi
Sucking lice
a. Damalinia equi
b. Haematopinus asini
b. Haematopinus asini
IBH
a. Culicoides
b. Culex pipiens
c. Tabanidae (horse and deer flies)
d. Simulium spp. (black flies)
a. Culicoides (BITING MIDGES)
Contact allergies
a. I
b. II
c. III
d. IV
d. IV
Pemphigus foliaceus
a. antibodies DSG-2 and DSG-4
b. antibodies DSG-1 and DSG-3
b. antibodies DSG-1 and DSG-3
Pemphigus folicaceus
a. Acanthocytes and degenerate neutrophils
b. Acanthocytes and non degenerate neutrophils
c. No acantholysis
b. Acanthocytes and non degenerate neutrophils
Pemphigus vulgaris
a. Acanthocytes and degenerate neutrophils
b. Acanthocytes and non degenerate neutrophils
c. No acantholysis
c. No acantholysis
Leukocytoclastic
a. neutrophil nuclei undergo karyorrhexis
b. neutrohil nuclei don’t undergo karyorrhexis
a. neutrophil nuclei undergo karyorrhexis
Better prognosis?
a. T-cell rich large B-cell lymphoma
b. T-cell lymphoma
a. T-cell rich large B-cell lymphoma
Pseudolymphomata
a. presence of lymphoid nodules and mast cells
b. presence of lymphoid nodules and B-lymfocytes
c. presence of lymphoid nodules and T-lymfocytes
d. presence of lymphoid nodules and eosinophils
d. presence of lymphoid nodules and eosinophils
Nodular necrobiosis
a. Equine axillary nodular necrosis
b. Eosinophilic granulomas
b. Eosinophilic granulomas
Hyperkalemia
a. peaked T
b. peaked P
c. shorter PR
d. shorter QRS
a. peaked T
Hyperkalemia
a. flattened T
b. shorter QRS
c. flattened P
d. shorter PR
c. flattened P
Hyperkalemia
a. prolonged QRS
b. shorter PR
c. peaked P
d. flattened T
a. prolonged QRS
Hyperkalemia
a. shorter QRS
b. prolonged PR
c. peaked P
d. flattened T
b. prolonged PR
HCO3- reabsorption in proximal CT
a. Na dependent
b. not Na dependent
a. Na dependent
HCO3- reabsorption in CD
a. Na dependent
b. not Na dependent
b. not Na dependent
Aldosterone
a. produced in response to high BP in adrenal medulla
b. produceed in response to high BP in adrenal cortex
c. produced in response to low BP in adrenal medulla
d. produced in response to low BP in adrenal cortex
d. produced in response to low BP in adrenal cortex
Prorenin
a. produced by proximal tubular cells
b. produced by distal tubular cells
c. produced by juxtaglomerular cells in afferent arterioles
d. produced by juxtaglomerular cells in efferent arterioles
c. produced by juxtaglomerular cells in afferent arterioles
Liver excretes
a. renin
b. angiotensin I
c. angiotensin II
d. angiotensinogen
d. angiotensinogen
Angiotensin II
a. systemic vasoconstriction
b. systemic vasodilation
a. systemic vasoconstriction
Angiotensin II
a. increased baroreflex
b. reduced baroreflex
b. reduced baroreflex
Angiotensin II
a. increased ADH
b. decreased ADH
a. increased ADH
Angiotensin II
a. increased aldosteron release
b. decreased aldosteron release
a. increased aldosteron release
PTH vs. vit D
a. PTH converts vit D to active forms
b. PTH converts vit D to non-active forms
c. Vit D converts PTH to active forms
d. Vit D converts PTH to non-active forms
a. PTH converts vit D to active forms
Primary hyperparathyroidism
a. increased PTH/Ca
b. decreased PTH/Ca
c. increased PTH / decreased calcium
d. decreased PTH / increased calcium
a. increased PTH/Ca
Vit D deficiency
a. higher Ca
b. lower Ca
b. lower Ca
Secondary hyperparathyroidism
a. vit D higher or CRF
b. vit D lower or CRF
b. vit D lower or CRF
Secondary hyperparathyroidism with vit. D deficiency
a. higher PTH
b. normal PTH
c. lower PTH
a. higher PTH
Secondary hyperparathyroidism with CRF
a. higher PTH
b. normal PTH
c. lower PTH
b. normal PTH (Serum PTH con centrations in horses with CRF and hypercalcemia are often in the normal range.)
Secondary nutritional hyperparathyroidism
a. diet low in Ca/PO4 or high in oxalate
b. diet low in Ca, high in PO4 and high in nitrate
c. diet low in Ca, high in PO4 and high in oxalate
d. diet low in Ca/PO4 and high in nitrate
c. diet low in Ca, high in PO4 and high in oxalate
Increase vit D due to
a. PTH, low PO4
b. Ca, 1,25[OH]2D, FGF 23
a. PTH, low PO4
Vit D
a. increase Ca absorption/reabsorption and increase PO4 reabsorption
b. increase Ca absorption/reabsorption and decrease PO4 reabsorption
c. decrease Ca absorption/reabsorption and decrease PO4 reabsorption
d. decrease Ca absorption/reabsorption and increase PO4 reabsorption
a. increase Ca absorption/reabsorption and increase PO4 reabsorption
Hypercalcemia
a. high PO4
b. normal PO4
c. low PO4
a. high PO4
Hypoparathyroidism
a. low PTH, low Ca/PO4/Mg
b. low PTH, low Ca/Mg, high PO4
c. low PTH, low Ca, high PO4/Mg
d. low PTH, low Ca/PO4, high Mg
b. low PTH, low Ca/Mg, high PO4
PTH higher in response to
a. hypervitaminose D
b. hyper Ca
c. hyper PO4
d. hyper Mg
c. hyper PO4
Predispose nutritional hyperparathyroidism
a. Ca:PO4 <1:2
b. Ca:PO4 >1:2
c. Ca:PO4 <1:3
d. Ca:PO4 >1:3
c. Ca:PO4 <1:3
Goiter
a. hypothyroidism
b. hypoparathyroidism
c. hyperthryoidism
d. hyperparathyroidism
a. hypothyroidism
Congenital hypothyroidism outbreaks
a. high nitrate
b. high oxalate
a. high nitrate
AVP and…
a. GH
b. TRH
c. CRH
d. ACTH
c. CRH
Feedback back to hypothalamus
a. T3/T4
b. cortisol
b. cortisol
Primary adrenal insufficiency
a. adrenal gland cortex
b. adrenal gland medulla
c. pituitary gland
d. hypothalamus
a. adrenal gland cortex
Secondary adrenal insufficiency
a. adrenal gland cortex
b. adrenal gland medulla
c. pituitary gland
d. hypothalamus
c. pituitary gland
Tertiairy adrenal insufficiency
a. adrenal gland cortex
b. adrenal gland medulla
c. pituitary gland
d. hypothalamus
d. hypothalamus
CIRC
a. ACTH
b. ACTH stimulation test
c. dexamethason suppression test
d. CRH stimulation test
b. ACTH stimulation test
PPID
a. pars intermedia
b. pars nervosa
c. pars medulla
a. pars intermedia
TRH stimulation test for PPID
a. higher sensitivity
b. higher specificity
c. lower sensitivity
d. lower specificity
a. higher sensitivity
Macula densa senses changes in [Na] in
a. PCT
b. DCT
c. CD
b. DCT
GFR lower
a. afferent/efferent vasoconstriction
b. afferent/efferent vasodilation
c. afferent vasoconstriction, efferent vasodilation
d. afferent vasodilation, efferent vasoconstriction
d. afferent vasodilation, efferent vasoconstriction
Permable for H2O
a. descending loop
b. ascending loop
a. descending loop
Impermeable for H2O
a. descending loop
b. ascending loop
b. ascending loop
Reabsorb Na + H2O (via aldosteron/vasopressin)
a. priniciple cells
b. intercalated cells
a. priniciple cells
Type A intercalated cells
a. important in acidosis
b. important in alkalosis
a. important in acidosis
Type B intercalated cells
a. important in acidosis
b. important in alkalosis
b. important in alkalosis
Type A intercalated cells
a. K/HCO3 secretion, H reabsorption
b. K/HCO3 reabsorption, H secretion
b. K/HCO3 reabsorption, H secretion
Type B intercalated cells
a. K/HCO3 secretion, H reabsorption
b. K/HCO3 reabsorption, H secretion
a. K/HCO3 secretion, H reabsorption
Aldosterone
a. increased HCO3 production in DCT cells
b. decreased HCO3 production in DCT cells
a. increased HCO3 production in DCT cells
Epineprhine / endothelin
a. constrict arterioles, increase Na reabsorption, increase RAAS
b. inhibits Na reabsorption, inhibits renin, increased in CHF
a. constrict arterioles, increase Na reabsorption, increase RAAS
ANP
a. constrict arterioles, increase Na reabsorption, increase RAAS
b. inhibits Na reabsorption, inhibits renin, increased in CHF
b. inhibits Na reabsorption, inhibits renin, increased in CHF
Renal tubular acidosis type 1
a. Failure H+ secretion PT
b. Failure H+ secretion DT
c. Failure HCO3 resorption PT
d. Failure HCO3 resorption DT
b. Failure H+ secretion DT
Renal tubular acidosis type 2
a. Failure H+ secretion PT
b. Failure H+ secretion DT
c. Failure HCO3 resorption PT
d. Failure HCO3 resorption DT
c. Failure HCO3 resorption PT
Worst acidosis
a. Type 1 RTA
b. Type 2 RTA
a. Type 1 RTA
Worst hypokalemia
a. Type 1 RTA
b. Type 2 RTA
a. Type 1 RTA
Glucosuria, proteinuria
a. Type 1 RTA
b. Type 2 RTA
b. Type 2 RTA (OFTEN)
Urine pH in severe acidosis inappropriately high (in mild acidosis both inappropriately high
a. Type 1 RTA
b. Type 2 RTA
a. Type 1 RTA
Effect alkali administration
a. hypo K better
b. hypo K worse
b. hypo K worse
Highest amount of HCO3 needed
a. Type 1 RTA
b. Type 2 RTA
b. Type 2 RTA
Ammonium chloride –> no acidic pH
a. Type 1 RTA
b. Type 2 RTA
a. Type 1 RTA
Ammonium chloride –> acidic pH
a. Type 1 RTA
b. Type 2 RTA
b. Type 2 RTA
Bicarbonate loading challenge –> reabsorbed
a. Type 1 RTA
b. Type 2 RTA
a. Type 1 RTA
Bicarbonate loading challenge –> lost in urine
a. Type 1 RTA
b. Type 2 RTA
b. Type 2 RTA
Low vit D
a. low Ca/PO4
b. high Ca/PO4
c. high Ca, low PO4
d. low Ca, high PO4
c. high Ca, low PO4 (DUE TO PTH INCREASE –> HIGHER CA BUT NOT HIGHER P)
ARF
a. low Ca/PO4
b. high Ca/PO4
c. high Ca, low PO4
d. low Ca, high PO4
d. low Ca, high PO4
CRF
a. low Ca/PO4
b. high Ca/PO4
c. high Ca, low PO4
d. low Ca, high PO4
c. high Ca, low PO4
PO4 lower
a. sepsis, high carbohydrate, hyperglycemia, insulin, starvation, refeeding, hyperlipemia, PN
b. renal injury, hypoparathyroidism, vit D toxicity, metabolic acidosis, cell lysis
a. sepsis, high carbohydrate, hyperglycemia, insulin, starvation, refeeding, hyperlipemia, PN
PO4 higher
a. sepsis, high carbohydrate, hyperglycemia, insulin, starvation, refeeding, hyperlipemia, PN
b. renal injury, hypoparathyroidism, vit D toxicity, metabolic acidosis, cell lysis
b. renal injury, hypoparathyroidism, vit D toxicity, metabolic acidosis, cell lysis
Pseudohyperphosphatemia
a. sepsis
b. high carbohydrate
c. hyperglycemia
d. insulin
e. starvation
f. refeeding
g. hyperlipemia
h. PN
i. renal injury
j. hypoparathyroidism
k. vit D toxicity
l. metabolic acidosis
m. cell lysis
m. cell lysis
PO4 higher
a. high Ca
b. low Ca
b. low Ca
Pheochromocytoma
a. chromaffin cells adrenal medulla
b. chromaffin cells adrenal cortex
c. mysosin cells adrenal medulla
d. mysosin cells adrenal cortex
a. chromaffin cells adrenal medulla
Insulin
a. alpha
b. beta
b. beta
Glucagon
a. alpha
b. beta
a. alpha