General Flashcards

1
Q

What will the main functional consequence be if half of the number of ribbon synapses in an inner hair cell degenerate?

A

The cell would not be able to encode the full range of sound intensity

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2
Q

ice with mutated and malfunctional Cav1.3 Ca2+ channels are deaf because:-

A

There is no neurotransmitter release from the hair cells

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3
Q

he inner hair cell resting transducer current is important because

A

It sustains a level of afferent activity that can be reduced or increased

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4
Q

What is the main difference in the mechanism responsible for detecting binaural timing differences in mammals and birds?

A

b. In mammals they are represented by two hemispheric channels and in birds by labelled lines

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5
Q

How does olfaction differs from other sensory modalities

A

The physical characteristics of light and sound can be described quantitatively along a few dimensions, whereas odorant molecules cannot.

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6
Q

You are investigating the role of local inhibitory neurons in the mouse olfactory bulb, and you test their role by blocking synaptic transmission in these neurons, preventing them from signalling to other neurons. Which of these would you predict would happen (compared to wildtype mice)?

A

Mice would be less able to behaviourally discriminate between different odours

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7
Q

Which of these techniques revealed that the Drosophila mushroom body is tiled by non-overlapping compartments defined by innervation by mushroom body output neurons (MBONs) and dopaminergic neurons (DANs)?

A

d. GAL4/UAS system

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8
Q

Which of the following would be experimental evidence that a neuron (or group of neurons) is acting to accumulate sensory evidence according to the drift-diffusion model of sensory decision-making?

A

d. Its activity ramps up over time, reaching a threshold immediately before the animal makes a decision.

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9
Q

The inner plexiform layer (IPL) contains synapses between:

A

bipolar, amacrine and ganglion cells

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