Geneesmiddelen En Neurotansmitters Flashcards

1
Q

GABA

A

Inhiberende aminozuurneurotransmitter

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2
Q

Ketoglutaarzuur

A

Precursor aanmaak GABA

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3
Q

Glutaminezuur

A

Exciterende aminozuurneurotransmitter + tussenproduct/ precursor synthese GABA

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4
Q

Vigabatrine

A

C4 gemodificeerd GABA-TRANSAMINASE inhibitor

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5
Q

Gabaculine

A

Cyclische GABA-TRANSAMINASE inhibitor

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6
Q

Isogabaculine

A

Cyclische GABA-TRANSAMINASE inhibitor

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7
Q

Valproïnezuur

A

Barnsteenzuur semi-aldehyde dehydrogenase inhibtor

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8
Q

Progabid

A

Prodrug voor GABA

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9
Q

Nipecotinezuur

A

GABA reuptake inhibitor thv neuronen en gliacellen

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10
Q

Guvacine

A

GABA reuptake inhibitor thv neuronen en gliacellen

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11
Q

THPO

A

GABA reuptake inhibitor thv gliacellen

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12
Q

THAO

A

GABA reuptake inhibitor thv gliacellen

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13
Q

Muscimol

A

GABA-A agonist

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14
Q

Methylmuscimol

A

GABA-A agonist

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15
Q

Dihydromuscimol

A

GABA-A agonist

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16
Q

Thiomuscimol

A

GABA-A agonist

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17
Q

Isuguvacine

A

GABA-A agonist

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18
Q

THIP

A

GABA-A agonist

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19
Q

P4C

A

GABA-A agonist

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20
Q

Bicuculine methochloride

A

GABA-A antagonist

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21
Q

DPB-THPO

A

GABA reuptake inhibitor

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22
Q

Baclofen

A

GABA-B agonist

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23
Q

Phaclofen

A

GABA-B antagonist

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24
Q

Tiagabine

A

GABA reuptake inhibitor thv neuronen en gliacellen

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25
Diazepam
Benzodiazepine
26
Carboline-ester
Inverse agonist benzodiazepines
27
Flumazenil
Benzodiazepine antagonist
28
Midazolam
Benzodiazepine
29
Medazepam
Benzodiazepine
30
Tetrazepam
Benzodiazepine
31
Alprazolam
Benzodiazepine
32
Clotiazepam
Benzodiazepine
33
Bromazepam
Benzodiazepine
34
Nordiazepam
Benzodiazepine
35
Chlordiazepoxide
Benzodiazepine
36
Ketazolam
Benzodiazepine
37
Triazolam
Benzodiazepine
38
Zolpidem
Z-product
39
Zopiclon
Z-product
40
Acetylcholine
NT —> ligand voor nicotine en muscarine receptoren
41
Nicotine
Natuurlijk ligand voor nicotinereceptoren
42
Muscarine
Natuurlijk ligand voor de muscarine receptor
43
Atropine
Natuurlijke antagonist voor de muscarine receptor
44
XANOMELINE
M1 agonist
45
Pirenzepine
M1 antagonist
46
AF-DX 166
M2 antagonist
47
Ganglionblokkers
Nicotinereceptor antagonist
48
Succinylcholine
Depolariserende neuromusculaire blokker —> nicotine receptor antagonist
49
Decamethonium
Leptocurares —> nicotinereceptor antagonist
50
Tubocurarine
Niet-depolariserende neuromusculaire blokker (pachycurares) —> nicotinereceptor antagonist
51
Pancuronium
Niet-depolariserende neuromusculaire blokker (pachycurares) —> nicotinereceptor antagonist
52
Vecuronium
Niet-depolariserende neuromusculaire blokker (pachycurares) —> nicotinereceptor antagonist
53
Rocuronium
Niet-depolariserende neuromusculaire blokker (pachycurares) —> nicotinereceptor antagonist
54
Gallamine
Niet-depolariserende neuromusculaire blokker (pachycurares) —> nicotinereceptor antagonist
55
Cisatracurium
Niet-depolariserende neuromusculaire blokker (pachycurares) —> nicotinereceptor antagonist
56
Mivacurium
Niet-depolariserende neuromusculaire blokker (pachycurares) —> nicotinereceptor antagonist
57
Neostigmine
Acetylcholinesterase inhibitor
58
Suggamadex
Herhaal
59
Cocoaine (zenuwstelsel)
Lokaal anestheticum - ester
60
Procaine
Lokaal anestheticum - ester
61
Benzoyltropine
Lokaal anestheticum - ester
62
Benzocaine
Lokaal anestheticum - ester
63
Lidocaine
Lokaal anestheticum - amide
64
Bupivacaine
Lokaal anestheticum - amide
65
Ropivaceine
Lokaal anestheticum - amide