Gene Linkage Practice Questions Flashcards

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1
Q

What does it mean for two genes to be “linked”?

o A) They are on the same chromosome.
o B) They assort independently.
o C) They are always inherited together.
o D) They are located on sex chromosomes.
o E) They exhibit quantum entanglement.

A

o A) They are on the same chromosome.

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2
Q

Linked genes:

o A) Always show a 9:3:3:1 ratio in dihybrid crosses.
o B) Are located on different chromosomes.
o C) Deviate from expected Mendelian ratios due to crossing over.
o D) Cannot undergo recombination.
o E) Are always purchased at the same time and have no refunds

A

o C) Deviate from expected Mendelian ratios due to crossing over.

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3
Q

What is a locus?

o A) A point where chromosomes cross over.
o B) The physical position of a gene on a chromosome.
o C) A pair of homologous chromosomes.
o D) The recombination frequency of a gene.
o E) A type of insect

A

o B) The physical position of a gene on a chromosome.

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4
Q

Which factor increases the likelihood of recombination between two genes?

o A) The genes are located closer together.
o B) The genes are located farther apart.
o C) The genes are on different chromosomes.
o D) Recombination frequency is unaffected by distance

A

o B) The genes are located farther apart.

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5
Q

The unit of measurement for genetic distance is:

o A) Kilobase pairs.
o B) Centimorgan (cM).
o C) Map frequency.
o D) Mendel unit.
o E) How many arguments occur at thanksgiving.

A

o B) Centimorgan (cM).

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6
Q

In a test cross of two unlinked genes, the expected progeny ratio is:

o A) 9:3:3:1.
o B) 3:1.
o C) 1:1:1:1.
o D) 1:2:1.

A

o C) 1:1:1:1.

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7
Q

For two linked genes, the test cross progeny ratios will:

o A) Always show equal proportions.
o B) Deviate from a 1:1:1:1 ratio.
o C) Exhibit no recombinants.
o D) Follow Mendel’s law of independent assortment

A

o B) Deviate from a 1:1:1:1 ratio.

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8
Q

If recombination frequency is 20%, what does this indicate?

o A) The genes are unlinked.
o B) The genes are close together.
o C) The genes are 20 centimorgans apart.
o D) There are 20 crossovers.

A

o C) The genes are 20 centimorgans apart.

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9
Q

A double crossover:

o A) Produces only non-recombinant gametes.
o B) Restores parental combinations of alleles.
o C) Happens only in linked genes.
o D) Occurs between sex chromosomes.
o E) Is required for proper tying of one’s shoes

A

o B) Restores parental combinations of alleles.

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10
Q

What is the relationship between recombination frequency and physical distance on a chromosome?

o A) Direct relationship.
o B) Inverse relationship.
o C) No relationship.
o D) Random correlation

A

o A) Direct relationship.

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11
Q

Which chromosome carries most sex-linked traits in humans?

o A) X chromosome.
o B) Y chromosome.
o C) Both X and Y equally.
o D) Neither; they are autosomal.

A

o A) X chromosome.

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12
Q

X-linked recessive traits are more commonly observed in:

o A) Females because they have two X chromosomes.
o B) Males because they have only one X chromosome.
o C) Both sexes equally.
o D) Individuals with Turner syndrome.

A

o B) Males because they have only one X chromosome.

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13
Q

Which gene determines male development in humans?

o A) SRY gene.
o B) TDF gene.
o C) XIST gene.
o D) Barr body.
o E) Gene Simmons.

A

o A) SRY gene.

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14
Q

What is a Barr body?

o A) An inactive X chromosome in female cells.
o B) A site of recombination during meiosis.
o C) The SRY gene product.
o D) A condensed Y chromosome.
o E) Similar to a pub body, but a bit more festive.

A

o A) An inactive X chromosome in female cells.

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15
Q

Calico coat patterns in cats result from:

o A) Autosomal dominant inheritance.
o B) X-linked inactivation.
o C) Polygenic inheritance.
o D) Codominance.
o E) Nobody really knows.

A

o B) X-linked inactivation.

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16
Q

What type of analysis is used to study inheritance patterns in families?

o A) Test cross.
o B) Pedigree analysis.
o C) Linkage mapping.
o D) DNA sequencing.
o E) Back-of-the-envelope calculations.

A

o B) Pedigree analysis.

17
Q

Autosomal recessive inheritance:

o A) Affects only males.
o B) Both sexes are equally affected.
o C) Traits appear only in every generation.
o D) Traits are located on the X chromosome.

A

o B) Both sexes are equally affected.

18
Q

In X-linked inheritance, a carrier female can pass the recessive allele to:

o A) Only her sons.
o B) Only her daughters.
o C) Both sons and daughters.
o D) Neither sons nor daughters.

A

o C) Both sons and daughters.

19
Q

What is the primary reason humans cannot be used for genetic experiments like other organisms?

o A) Humans have too many chromosomes.
o B) Ethical and practical concerns.
o C) Humans lack observable phenotypes.
o D) Linkage cannot be studied in humans.
o E) They are too busy.

A

o B) Ethical and practical concerns.