gastrulation + neurulation Flashcards

exam 1

1
Q

formation of the three germ layers

A

gastrulation

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2
Q

what is the first step in gastrulation?

A

formation of the primitive streak from the caudal end to the head end

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3
Q

what happens after the formation of the primitive streak

A

there is a waterfall like rush of ectoderm cells through it and this will become the mesoderm

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4
Q

what does the mesodorm form?

A

notochord

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5
Q

what does the notochord do?

A

helps define the major axis of our bodies and later becomes the invertebral disk

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6
Q

what is the process of neurulation?

A

process in which the neural plate folds to form the neural tube and crest

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7
Q

neural plate is a

A

flat piece of the ectoderm

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8
Q

what induces the formation of the neural tube?

A

notochord

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9
Q

mesoderm cells differentiate into

A

somites

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10
Q

somites

A

precursor of the axial skeleton/ skeletal muscles

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11
Q

somitogenesis

A

process of segmentation of the paraxial mesoderm

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12
Q

how does somitogenesis occurs?

A

begins cranially and extends caudally adding a somite pair and the process is sequential

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13
Q

neural crest cells become the

A

PNS

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14
Q

neural tube becomes the

A

CNS

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15
Q

lateral late mesoderm

A
  1. splanchic
  2. somatic
  3. extra-embryonic
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16
Q

intermediate mesoderm

A
  1. kidney

2. Gonads

17
Q

paraxial somitic mesoderm

A
  1. sclerotome
  2. syndotome
  3. myotome
  4. endothelial cells
  5. dermatome
18
Q

syndotome

A

tendons

19
Q

sclerotome

A

cartilage

20
Q

dermetome

A

skeletal muscle

21
Q

What is so special about myotomes?

A

split by the tranverse processes

22
Q

Myotomes are split into two catergories

A
  1. epimere

2. hypomere

23
Q

epimere

A

dorsal/ back musculature

24
Q

hypomere

A

ventral body and all limb musculature

25
Q

faulty crest migration—-? vagal crest into distal gut

A

DiGeorge

26
Q

bowel nerve cell are not present—-> no neural crest migration leading to a congenital megacolon

A

Hirchspung’s dx

27
Q

anterior failure to close neural tube

A

anencephaly

28
Q

posterior failure to close neural tube but there is no potrusion of fluid

A

spina bifida occulta

29
Q

spina bifida cystica which has swelling of the meninges

A

meningocele

30
Q

spina bifida cystica which has swelling of the meninges and spinal cord

A

meningomyelocele