gastrulation + neurulation Flashcards

exam 1

1
Q

formation of the three germ layers

A

gastrulation

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2
Q

what is the first step in gastrulation?

A

formation of the primitive streak from the caudal end to the head end

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3
Q

what happens after the formation of the primitive streak

A

there is a waterfall like rush of ectoderm cells through it and this will become the mesoderm

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4
Q

what does the mesodorm form?

A

notochord

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5
Q

what does the notochord do?

A

helps define the major axis of our bodies and later becomes the invertebral disk

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6
Q

what is the process of neurulation?

A

process in which the neural plate folds to form the neural tube and crest

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7
Q

neural plate is a

A

flat piece of the ectoderm

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8
Q

what induces the formation of the neural tube?

A

notochord

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9
Q

mesoderm cells differentiate into

A

somites

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10
Q

somites

A

precursor of the axial skeleton/ skeletal muscles

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11
Q

somitogenesis

A

process of segmentation of the paraxial mesoderm

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12
Q

how does somitogenesis occurs?

A

begins cranially and extends caudally adding a somite pair and the process is sequential

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13
Q

neural crest cells become the

A

PNS

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14
Q

neural tube becomes the

A

CNS

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15
Q

lateral late mesoderm

A
  1. splanchic
  2. somatic
  3. extra-embryonic
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16
Q

intermediate mesoderm

A
  1. kidney

2. Gonads

17
Q

paraxial somitic mesoderm

A
  1. sclerotome
  2. syndotome
  3. myotome
  4. endothelial cells
  5. dermatome
18
Q

syndotome

19
Q

sclerotome

20
Q

dermetome

A

skeletal muscle

21
Q

What is so special about myotomes?

A

split by the tranverse processes

22
Q

Myotomes are split into two catergories

A
  1. epimere

2. hypomere

23
Q

epimere

A

dorsal/ back musculature

24
Q

hypomere

A

ventral body and all limb musculature

25
faulty crest migration----? vagal crest into distal gut
DiGeorge
26
bowel nerve cell are not present----> no neural crest migration leading to a congenital megacolon
Hirchspung's dx
27
anterior failure to close neural tube
anencephaly
28
posterior failure to close neural tube but there is no potrusion of fluid
spina bifida occulta
29
spina bifida cystica which has swelling of the meninges
meningocele
30
spina bifida cystica which has swelling of the meninges and spinal cord
meningomyelocele