Gastrointestinal #2 Flashcards
How is appendicitis treated?
Low threshold to admit
Surgery
Abx: Metronidazole &Cefuroxime
Surgery: Appendicectomy
What are the signs of appendicitis in a child?
Rare <3yr Most common- Primary school age & teens Abdo pain-McBurney's point Low grade fever/pyrexia Anorexia Lying still/Flexed knees into tummy N&V Constipation Rovsing's sign: Palpate LIF causes pain in the RIF
What are the timings for the continuation of appendicitis?
6-12hr: Full thickness inflammation
24-36hr: Gangrenous & ?perforation- peritonitis
What is Coeliac disease associated with?
DM type 1
Down’s Syndrome
Juvenile chronic arthritis
What is the pathophysiology of Coeliac disease?
Autoimmune (T-cell mediated)
Enteropathy due to lifelong intolerance to gluten proteins
Bowel destruction in response to gluten
What are the signs & symptoms of Coeliac disease?
Diarrhoea Pale, floating stools Anorexia Irritable Fatigue Failure to thrive Late: Apathy, Gross motor delay, Ascites, Anaemia, Peripheral oedema, Delayed puberty Coeliac Crisis: Dehydration following malabsorption & diarrhoea
How is Coeliac disease investigated?
Serum Antigliadin Abx (IgA), tissue transglutaminase Abx
Faecal fat studies
S. bowel biopsy: Endoscopy shows diffuse subtotal villus atrophy, lymphocyte infiltration, crypt hyperplasia
How is Coeliac disease managed?
Gluten free diet (Villi return to normal)
What are the types of inguinal hernia?
Direct: Protrudes directly through a weakness in the posterior inguinal canal
Indirect: MOST COMMON, failure of inguinal canal to close after passage of testis in utero/neonatal. Sac passes through internal inguinal ring, along inguinal canal through patent processus vaginalis.
What is the treatment of inguinal hernias?
Repair via surgery
What is intussusception?
Part of the (small) bowel inserts into another part of the bowel causing obstruction
What is the pathophysiology of intussusception?
Infection (GE) leads to enlarged Peyer’s patches
Lymphatic tissue is leading edge pulling s.bowel into caecum
Results in obstruction
Where is intussusception most commonly seen?
Ileocaecal junction
Almost all happen when ileum folds into caecum
Who does intussusception usually affect?
Kids: 6m-2yr
Rarely adults
What are the causes of intussusception?
Idiopathic
Adults: Tumour, Meckle’s diverticulum