gastro Flashcards
This type of IBD has + risk of primary sclerosing cholangitis
UC - PSC is risk for cholangiocarcinoma
terminal ileum, skip lesions/discontinuous, fistulae, luminal stricture, granulomas
Chrons
Continuous mucosal lesions, confined to colon and rectum, Cured by colectomy, higher risk of colon cancer, pyoderma granulosum, erythema nodosum, p-ANCA, crypt abscesses
UC
extra-intestinal symptoms of crohns
uveitis, arthritis, AS, erythema nodosum, pyoderman gangrenosum, apthrous oral ulcers, chloelithiasis, nephrolithaisis
Half of all bile duct cancers are associated with this IBD
UC
This complication of UC is a surgical emergency
toxic megacolon
surgery is often curative for this IBD
UC
Copper of Wilson’s disease deposits in this part of the brain
basal ganglia
reduced stool osmotic gap + larger stool colume
secretory diarrhea
elevated stool osmotic gap, lactose intolerance
osmotic diarrhea
UC + fatigue, pruritus, elevated alk phos
PSC
Labs to determine active HBV infection
HBsAg and anti-HBc
periumbilical abdominal pain out of proprtion to examination, nausea, vomiting in elderly person
mesenteric ishcmia
What is HBV status of somenoe with + HBV surface antibody but NO HBV surage antigen
immunized
chronic abdominal pain + diarrhea and/or constipation, relief of pain with BM, no bloody stools, normal intestinal mucosa
IBS
colicky abdominal pain, chronic diarrhea with bloody stool, weight loss, crypt abscess
UC
triad for diagnosis of ALF
elevated aminotransferease hepatic encelpaholopathy (confusion, smonolence, flapping tremor) liver synthesis dysfunction - INR, platelets
When TIPS for cirrhosis
ascites that does not respond to diuretics or ongoing bleeding after variceal clamping
chronic diarrhea, steatorrhea, weight loss, atrophy of intestinal villi
celiac disease
With the D-xylose test in celiac pt, do you expect D-xylose urine and venous blood level to be low?
yes, because damage to small bowel. would expect normal if malabosprtion issue to deficiency (chronic pancreatitis
What two things does GERD predispose you to
Barrett’s and esophageal strictures
dysphagia to solids and liquids
achalasia
Does hyperprolactin INHIBIT GnRH mediated release of FSH and LH?
Yep, but doesn’t affect TSH
multiple duodenal ulcers + chronic diarrhea + malabsorption
ZES with gastrinoma - increased acid inactivates pancreatic enzymes
lynch syndrome cancers
colorectal and endometrial
parathyroid, pituitary and pancreatic adenomas
MEN1
hydrogen breath test
stool test for reducing substances
low stool pH
increased stool osmotic gap
lactose intolerase
macrocytic anemia, hypersegmented neutrophils
folate deficiency
would someone immunized against HBV have anti-HBc?
no, because vaccine doesn’t have core Ag, someone immunized has anti-HBs ONLY
villous atrophy, malabsorption, iron deficiency anemia, Iga anti-endomysial and anti-tissue transglutaminas Ab
Celiac
multiple portions of GI tract, rectal sparing, presence of noncaseating granulomas, fistula formations
Crohns
recurrent bouts of upper abdominal pain, radiate to back, relieved when leaning forward, diarrhea/steatorrhea, weight loss, pancreatic calcifications
chronic pancreatitis
sudden loss of vision and onset of floaters
vitreous hemorrhage, diabetic retinopathy
painless progressive blurring of central vision
macular degeneration
sudden painless unilateral loss of vision
central retinal vein occlusion
disk swlling, venous dilation and tortuosity, retinal hemorrhages, cotton wool spots
central retinal vein occlusion
previous GSW, infection with encapsulated bacteria (h flu, s pneumo), NO anti-body mediated phagocytosis
splenectomy
