Gastritis Flashcards
1
Q
Aetiology?
A
A= Auto-immune
B=Bacterial
C= Chemical
2
Q
Pathology?
A
Auto-immune:
auto-antibodies against parietal cells –> inflammation of gastric mucosa
Bacterial:
H. Pylori
Chemical:
NSAIDs/ Bile
3
Q
Tests?
A
mainly for H.Pylori:
- serology–> elevated IgG
- urea breath test
4
Q
Treatment?
A
Pharmacological:
PPI/ H2 antagonist / H.Pylori eradication therapy
5
Q
what is a side-effect of auto-immune gastritis?
A
pernicious anaemia
reduced gastric productioin of HCl and intrinsic factor by parietal cells so no B12 absorption –> pernicious anaemia