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systems- GI > Gastric Secretion > Flashcards

Gastric Secretion Flashcards

1
Q

what is the fundus?

A

he part of a hollow organ ) that is furthest from the opening.

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2
Q

what is the function of the fundus?

A

storage

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3
Q

what is the function of the body of the stomach?

A 
Storage
Mucus
HCl
Pepsinogen
Intrinsic factor
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4
Q

what is the function of the antrum?

A

Mixing/Grinding

Gastrin

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5
Q

what are the cellular composition of gastric glands?

A

mucous neck cells
cheif cells
parietal cells

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6
Q

what does the mucous neck cells secrete?

A

mucus

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7
Q

what do the cheif cells secrete?

A

pepsinogens

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8
Q

what do the parietal cells secrete?

A

HCL and intrinsic factor

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9
Q

what is the ph of the blood?

A

7.4

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10
Q

what is the ph of the stomach?

A

less than 2

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11
Q

what enzyme converts H2CO3 to water and co2 inside the cells?

A

carbonic anhydrase

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12
Q

what is gastric acid secretion controlled by?

A

Neurocrine (vagus/local reflexes)

Endocrine (gastrin)

Paracrine (histamine)

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13
Q

what are the hormones released from gland cells in duodenal mucosa?

A

secretin, cholecystokinin, GIP

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14
Q

enterogastrones are released in response to what?

A

acid, hypertonic solutions, fatty acids or monoglycerides in duodenum

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15
Q

what is the function of enterogastrones?

A

act collectively to prevent further acid build up in duodenum

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16
Q

what are the two strategies of enterogastrones preventing further acid build up?

A

inhibit gastric acid secretion

reduce gastric emptying (inhibit motility/contract pyloric sphincter)

17
Q

what is pepsinogen secreted by?

A

cheif cells

18
Q

what is the function of zymogen storage?

A

prevents cellular digestion

19
Q

when is pepsins inactivated?

A

at neutral pH

20
Q

what is gastric mucus produced by?

A

by surface epithelial cells and mucus neck cells

21
Q

what is the cytoprotective role?

A

protects mucosal surface from mechanical injury

22
Q

why is a neutral pH significant in the cytoprotective role?

A

protects against gastric acid corrosion and pepsin digestion

23
Q

what are intrinsic factors produced by?

A

parietal cells

24
Q

what are intrinsic factors required for?

A

vitamin b12 absorption

25
Q

what is an example of intrinsic factor defect?

A

pernicious

systems- GI (40 decks)

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