alcohol related disease Flashcards
what is steatosis?
fatty liver
what is steatohepatitis?
fatty liver inflammatioon
signs of chronic liver disease
Spider naevi, palmar erythema, gynaecomastia, loss of axillary and pubic hair, ascites, encephalopathy
Jaundice
Muscle wasting
causes of hepatic encephalopathy
infection drugs constipation GI bleed electrolyte disturbance
treatment of hepatic encephalopathy
Bowel clear out, lactulose, enemas. Antibiotics Supportive ITU, airway support Nasogastric tube for meds
symptoms of spontaneous bacterial peritonitis
abdominal pain, fever, rigors
signs of spontaneous bacterial peritonitis
sepsis, tachycardia, temperature
what is an ascitic tap?
An ascitic tap is a medical procedure where a needle is used to drain fluid that is trapped in an internal body cavity, most commonly the abdomen
how does alcohol hepatitis present?
Jaundice Encephalopathy Infection common Decompensated hepatic function (Low albumin and raised prothrombin time/INR)
how to diagnose alcoholic hepatitis
Raised Bilirubin
Raised GGT and AlkP
Alcohol History
Exclude other causes
treatment of alcoholic hepatitis
Supportive Treat infection Treat encephalopathy Treat alcohol withdrawal Protect against GI bleeding Airway Protection / ITU care
when would you use steroids to treat alcoholic hepatitis?
only if grading severe and glasgow alcoholic hepatitis score is over 9
treatment of steatohepatitis?
weight loss, excersise
investigation for steatohepatitis?
Fatty liver on USS
Liver Biopsy
Raised Alanine amino transferase