Gametogenesis II Flashcards
Initial Rapid transport of sperm in Cervical canal
- 5->20 minutes following ejaculation
- relies mostly on muscular movements of FEMALE
- NOT as capable of fertilizing
Acrosomal Phase of Spermatogenesis
- Rotation of sperm so Acrosomal pole faces seminiferous tubule
- Cytoplasm displaced toward tail
Ampulla
- “Handle” portion of the Fallopian tubes
- Site of SLOW transport
72 hours
Major Acrosomal enzymes
- Hyaluronidase
- Zona Lysin
LH interactions of Sperm Cells
- LH from AP bind to Leydig cells
- Leydig cells synthesize Testosterone
- Testosterone carried to the bone to Sertoli cells and other sexual tissue
Sperm are capable of fertilization by the time they reach the ______ of the Epididymis.
TAIL
Purpose of Leydig cells?
Produce Testosterone
Slow transport of sperm in Cervical canal
- 2->3 mm per hour
- Involves swimming through cervical mucous
- may reach oviducts in 2-4 days
How is the egg transported to the Uterus?
Mostly through smooth muscle contractions
Cap Phase of Spermatogenesis
Mature acrosome forms a CAP over the Nucleus
The Primitive sex cords turn into what?
Seminiferous tubules
Golgi Phase of Spermatogenesis
- Proacrosomal vesicles
- Acrosomal vesicles
Fimbriae of the uterine Tube is also known as what?
Catchers mitt
pH change in the Vagina one it come in contact with sperm?
- Upper Vagina
- Cervix
- 4.3 ———> 7.2
2. 6 ————> 6.5
Optimal for sperm motility
Passive Sperm Transport occurs via what?
- Testicular fluid
- Smooth muscle contraction
- Cilia from seminiferous tubules
What is required for rapid transport of the egg to the uterus?
Progesterone
Why do men produce sperm throughout their life?
- STEM cells responsible for the production of sperm
- Cells remain viable for the life of the individual
Fertilization typically occurs where?
In the AMPULLA
Function of Sertoli cells
- Support and Maintenance
- Secrete ESTROGEN, Inhibin and anti-Mullerian factor
- Maintain Blood Testis barrier
- Secrete Tubular fluid
- Phagocytize residual bodies of sperm cells
Maturation Phase of Spermatogenesis
- Completion of Flagellum
- Completion of Nuclear Condensation
FSH interactions of Sperm Cells
- FSH from AP binds to SERTOLI cells
- Convert Testosterone to Estrogen
- Sertoli cells produce androgen-binding protein
- Sertoli cells produce Inhibin
Ex of secondary sexual tissues
- Prostate
- Penis
- Ductus Deferens
- Epididymis
- Seminal Vesicle
- Scrotum
The immature sperm cells are more located _____ and the mature sperm cells are located _______.
- In the periphery
2. Towards the Lumen
Typical maturation period for Sperm cells in the Epididymis
12 days
How long does it take the egg to reach the Uterus?
3-4 days
Stages of Spermatogenesis
- Primordial Germ cell (2N)
- Spermatogonia (2N)
- Primary Spermatocyte (2N)
- Secondary Spermatocyte (N) x 2
- Spermatid (N) x 4
Primary vs Secondary Spermatogenesis
1:
- 2N
- First maturation division (Meiosis 1)
2:
- 1N x 2
- Second maturation division
(Meiosis 2)
Isthmus
- Portion of the Fallopian tubes closest to the uterus
- Site of Rapid transport
8 hours
