Fungi Flashcards
Facts surrounding fungi
500 cause human disease
100 cause infection in immunocompromised patients
Human infection can be caused by environment/ trauma, digestion, inhalation
. Some areas hold endemics and some fungi spread
The five types of fungi
Superficial mycoses
Subcutaneous mycoses
Deep mycoses caused by opportunist pathogens
Systemic mycoses caused by opportunistic pathogens
Systemic mycoses caused by primary pathogens
What can superficial mycoses be
. Tinea corpons . Tinea cruis . Tinea poeis . Onychomycosis . seborrhoeic dermis . Candida
What are three common types of candida caused by superficial mycoses
. Acute/ chronic oral mycosis - Candida albicans
. Vulvovaginitis- Candida albicans
. Cutaneous- candida parapsoris
What is an example of subcutaneous mycoses
Subcutaneous zygomycosis
What are two forms of subcutaneous zygomycosis
. Basidolomycosis
(Plants animal waste fruit bats)
. Rhinofacial condidobolmycosis
(Tropical rain forest- soil rotting veg)
What is a type of systemic mycoses caused by primary pathogens
Dimophric endemic pathogens
. Yeast at 37degree
. Immune system depends on survival
. Get from contact with nature
What are three examples of deep mycosis caused by opportunistic pathogens
. Fungal sinusitis
. Chronic pulmonary aspergillosis
. Fungal ball
What four diseases can systemic mycoses caused by opportunistic pathogens cause
Candida
Angioinvasive aspergillosis
Aspergillis SPP
Myormycosis
What is candida
Common fungal infection with 40% mortality
Candida albicans most common form
Who is at risk of suffering from candida and what can it lead to
Risk- cvc, gi surgery, immunosuppressed.
Lead to- eye and renal damage. Meningitis, arthritis, osteomylis, endocarditis.
What can aspergillis SPP cause
. Broncho pulmonary . Chronic pulmonary . Aspergilloma . Invasive aspergillosis . Rhinosinus . Burns infection
What is Myormycosis and who’s at risk
. Third most important with a rising mortality rate
. Have daily exposure not infectious normally- soil and decaying
. Grows at 37 degree
Risk- diabetic immunosuppressed prolonged neuropatia trauma
What diseases can come from mucormycosis and what’s the mortiskity rate
Rhinocerebral 67% Pulmonary 83% Cutsaneous 10% GI 100% CNS 100%
What is angioinvasion aspergillis
Causes dry cough and feaver
Bad in immunosuppressed
90% pulmonary
What do anti fungals and antibiotics aim to do
Kill the fungi without killing the host cell
What are fungi
1/6 life kingdoms
Eukarolytic, multi or singular cellular
. Ridgid cells wall glycoprotein/ polysaccharides
. 300 million serious cases annually
