Fungal Flashcards
1
Q
flucytosine mode of action
A
inhibits DNA and RNA biosynthesis by conversion to 5-flourouracil by cytosine deaminase
2
Q
antifungal that inhibits DNA synthesis
A
flucytosine
3
Q
side effects of flucytosine
A
myelosuppression
4
Q
aspergillus infection can increase risk of what type of cancer
A
hepatocellular carcinoma
(aspergilus induces TP53 mutations)
5
Q
‘soap bubble’ lesions in brain
A
cryptococcus neoforms infection
6
Q
patient with diabetes/neutropenia - headache, fever, sinositus, orbital pain, bloody-black nasal discharge
A
mucor spp.
7
Q
black necrotic eschcar in nose
A
mucormycosis - mucor and Rhizopus spp
