Fundementals Of Pathology (pg. 53-54) Flashcards

1
Q

What is atrophy?

A

Decrease in size

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2
Q

What is hypertrophy?

A

Increase in size

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3
Q

What is hyperplasia?

A

Increase in number

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4
Q

What is metaplasia?

A

One cell type to another

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5
Q

What is dysplasia?

A

Size shape and function change

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6
Q

What is anaplasia?

A

Disorganization or cancer

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7
Q

What is hypoplasia?

A

Defective development

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8
Q

What is aplasia?

A

Lack of development

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9
Q

What is agenesis?

A

Absence of growth

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10
Q

What type of degeneration is coagulation infarction?

A

Myocardial infarction

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11
Q

What type of degeneration is liquefaction?

A

Brain

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12
Q

What type of degeneration is Caseous?

A

TB

Single lesion=Ghons complex

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13
Q

What type of degeneration is enzymatic?

A

Head of pancreas

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14
Q

What type of degeneration is alveogon?

A

Tail of pancreas

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15
Q

What type of generation is fatty?

A

The liver

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16
Q

What type of degeneration is Gummatous?

A

Tertiary syphilis (in the brain)

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17
Q

What type of degeneration is wallerian?

A

Peripheral nerves (distal to proximal)

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18
Q

What type of immunity cells are liver cells?

A

Kupffer cells

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19
Q

What are the immunity cells for alveoli?

A

Alveolar macrophages

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20
Q

What type of immunity cells are in the brain?

A

Microglial cells

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21
Q

What type of immunity cells are in the tissues?

A

Histocytes or fixed macrophages

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22
Q

What type of immunity cells are in the lungs?

A

Dust cells

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23
Q

What is humoral immunity

A

Anti-body B cells

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24
Q

Where are you moral immunity cells found?

A

Spleen tonsils lymph, G.I. and bone marrow

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25
Where is cellular immunity cells found?
In the Thymus
26
What is cellular immunity?
Sensitized lymphocyte T cells
27
What does cellular immunity protect against?
Protect body from own defense system bacteria viruses and poisons
28
What is an IGA immunoglobulin?
Milk and membranes
29
What is characteristic about IgG immunoglobulins?
Smallest and most numerous
30
What is IGE associated with?
Allergies and parasites
31
What kind of response is an IgM?
The first response and is the largest
32
What is type one hypersensitivity?
Immediate
33
What is type 2 hypersensitivity?
Antibody mediated
34
What is type III hypersensitivity?
Immune
35
What is type four hypersensitivity?
T-cell mediated
36
What is the acronym for the four types of hypersensitivity's?
I am it
37
What type of white blood cell is a neutrophil?
A bacterial infection or acute infection, phagocytic
38
What type of WBC is a lymphocyte?
A viral infection or chronic disease
39
What type of WBC is a monocyte?
Chronic infection 5-8%
40
What type of WBC is an eosinophil??
Parasitic and allergic conditions 2-4%
41
What type of WBC is a basophil?
S similar to mast cells makes heparin and histamine 0-.5%
42
What is the acronym for white blood cell's or leukocytes?
``` never 60% let 30% my 8% engine 3% blow 0% ```
43
Which three conditions have ivory white vertebra?
1. Mets 2. Pagets 3. Hodgkins
44
What is another name for pagets disease?
Osteitis Deformas
45
What is associated with Hodgkin's lymphoma?
Reed Sternberg cell relapsing fever ivory white vertebra
46
What is brutons agammaglobulinemia?
The inability to produce antibiotics due to lack of B cells
47
What is multiple myeloma associated with?
Bence Jones proteinura Most common primary malignancy of the spine
48
What is aids and what conditions are associated with it?
It is a retrovirus that attacks T4 helper cells 1. Karposi sarcoma 2. Parasitic pneumonia
49
What is Hashimoto's?
An autoimmune disease most common hypothyroidism
50
What is unique about Burkitts lymphoma?
``` Has starry sky appearance is aggressive found in children Abdominal mass Epstein-Barr virus can be cured with chemo ```
51
What is present in all leukemia?
Anemia
52
What is acute lymphocytic or actuate lymphoblastic leukemia?
Similar to Burkitts lymphoma or starry cells peaks at 3 to 4 years old ALL
53
What is chronic myelocystic a.k.a. chronic granulocystic
CML- found in all ages peek at 40 to 50 years old chromosomal abnormality "Philadelphia chromosome"
54
What is active myeloblastic or acute granulocystic leukemia?
AML-most common in young adults peak is 15 to 20 years old
55
What is chronic lymphocytic leukemia?
CLL- found most commonly in elderly
56
What is Kwashiorkor disease?
And immunodeficiency disease Deficiency of protein only "potbelly" loss of muscle mass rare in US children however 50% elderly in nursing homes
57
What condition is Marasmus?
In immuno deficiency disease deficient of protein and calories WHO says 5 million children die each year from malnutrition
58
What is a protective response in acute inflammation and repair?
Leukocytes and platelets
59
What is a mediated response in acute inflammation and repair?
Chemical factors from plasma or cells
60
In regards to acute inflammation and repair what changes in vascular caliber?
An increase in blood flow
61
When do plasma proteins and leukocytes leave circulation?
During acute inflammation and repair
62
What are the steps of emmigration of leukocytes to injury
``` A. margination B. rolling C. tight adhesion D. Migration across vessel wall E. Migration to tissue ```
63
What is a chronic reaction to inflammation and repair?
Lymphocytes and macrophages (primary)
64
What are the signs of acute inflammation?
``` Rubor (red) Tumor (swollen) Callor (hot) Dolor (pain) Loss of function ```
65
What are the steps of inflammation and repair?
1. Transient vasoconstriction (few secs) 2. Vasodilation (increase bf) 3. Slowing of circulation A. Increased permeability, viscosity, and concentration of red cells (stasis) B. Neutrophils stick to endothelium C. Migrate to interstitial tissue and margination occurs
66
What are the chemical mediators to acute inflammation and repair?
``` Histamine- mast cells serotonin complement- 20 components Kinin- increases vascular permeability Clotting system ```