Functions of the Kidney Flashcards

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1
Q

What are the primary functions of the kidney?

A

Filtration of blood, removal of waste products, regulation of electrolytes, blood pressure, and volume, acid-base balance, and hormone production.

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2
Q

How do the kidneys regulate blood volume and blood pressure?

A

By adjusting the volume of urine produced and releasing renin to regulate blood pressure.

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3
Q

What role do the kidneys play in electrolyte balance?

A

By reabsorbing and excreting ions such as sodium, potassium, calcium, and phosphate.

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4
Q

How do the kidneys maintain acid-base balance in the body?

A

By excreting hydrogen ions and reabsorbing bicarbonate from urine.

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5
Q

Describe the process of glomerular filtration.

A

The process where blood is filtered in the glomerulus, allowing water and solutes to pass into the Bowman’s capsule.

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6
Q

What is the function of the renal tubules in urine formation?

A

The renal tubules reabsorb needed substances and secrete waste products into the urine.

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7
Q

How do the kidneys excrete metabolic waste products?

A

By filtering blood to remove urea, creatinine, and other waste products into the urine.

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8
Q

What is the role of the kidneys in water reabsorption?

A

By reabsorbing water from the filtrate back into the blood, primarily in the renal tubules and collecting ducts.

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9
Q

How does the renin-angiotensin-aldosterone system (RAAS) affect kidney function?

A

RAAS regulates blood pressure and fluid balance by controlling sodium and water reabsorption and vascular tone.

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10
Q

What is the significance of erythropoietin produced by the kidneys?

A

Erythropoietin stimulates red blood cell production in response to hypoxia.

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11
Q

How do the kidneys contribute to calcium and phosphate balance?

A

By regulating the reabsorption and excretion of calcium and phosphate ions.

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12
Q

What is the role of the kidneys in vitamin D metabolism?

A

The kidneys convert vitamin D into its active form, calcitriol, which is essential for calcium absorption.

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13
Q

How do the kidneys handle glucose reabsorption?

A

Glucose is reabsorbed in the proximal convoluted tubule via sodium-glucose transport proteins.

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14
Q

What mechanisms are involved in sodium reabsorption in the kidneys?

A

Sodium reabsorption involves active transport mechanisms in the proximal tubule, loop of Henle, distal tubule, and collecting duct.

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15
Q

How do the kidneys regulate potassium levels?

A

By secreting or reabsorbing potassium in the distal convoluted tubule and collecting duct.

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16
Q

Describe the process of tubular secretion.

A

Tubular secretion involves the active transport of substances from the blood into the tubular fluid.

17
Q

How do the kidneys remove drugs and toxins from the body?

A

By filtering the blood and secreting drugs and toxins into the urine for excretion.

18
Q

What is the countercurrent multiplication system in the kidneys?

A

A mechanism that creates a concentration gradient in the medulla, allowing the kidneys to produce concentrated urine.

19
Q

How does the kidney medulla contribute to urine concentration?

A

The medulla contains the loop of Henle and collecting ducts, which help concentrate urine by reabsorbing water.

20
Q

What role do the kidneys play in protein conservation?

A

By filtering and reabsorbing proteins to prevent their loss in urine.

21
Q

How do the kidneys respond to dehydration?

A

By conserving water through increased reabsorption in the collecting ducts, mediated by antidiuretic hormone (ADH).

22
Q

What is the importance of the glomerular filtration rate (GFR)?

A

GFR measures the rate at which blood is filtered in the glomeruli, indicating kidney function.

23
Q

How do the kidneys participate in blood detoxification?

A

By filtering and excreting toxins and metabolic waste products from the blood.

24
Q

What is the function of the juxtaglomerular apparatus in the kidneys?

A

The juxtaglomerular apparatus regulates blood pressure and GFR through the release of renin.

25
Q

How do the kidneys interact with the endocrine system?

A

The kidneys release hormones such as erythropoietin and renin, and convert vitamin D to its active form.

26
Q

How is blood flow regulated within the kidneys?

A

By autoregulation mechanisms that maintain consistent blood flow despite changes in systemic blood pressure.

27
Q

What are the functions of the proximal convoluted tubule?

A

Reabsorption of water, ions, and nutrients; secretion of wastes and excess ions.

28
Q

How does the loop of Henle contribute to the concentration of urine?

A

By creating a hyperosmotic medullary environment, facilitating water reabsorption from the collecting ducts.

29
Q

What are the functions of the distal convoluted tubule?

A

Reabsorption of sodium and calcium; secretion of potassium and hydrogen ions.

30
Q

How do the collecting ducts of the kidneys function in water reabsorption?

A

Collecting ducts reabsorb water and concentrate urine under the influence of ADH.