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Board Review > Foundations > Flashcards

Foundations Flashcards

1
Q

amino acids modified in Golgi apparatus

A

serine, threonine, asparagine

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2
Q

nuclear localization signals

A

proline, arginine, lysine

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3
Q

G1–>S

A

Cyclin D-CDK4

Cyclin E-CDK2

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4
Q

G2–>M2

A

Cyclin A-CDK2

Cyclin B-CDK1

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5
Q

target lysosomal protein

A

mannos-6-phosphate

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6
Q

important for phospholipids found in myelin and sythesized in peroxisomes

A

plasmalogen

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7
Q

mechanism of cell injury

A

ATP depletion, mitochondrial damage, influx of calcium, accumulation of oxygen-derived free radicals

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8
Q

irreversible cell injury

A

calcium influx, damage to plasma membrane, rupture of lysosome, mitochondrial permeability, pyknosis, karyolysis, karyorrhexis

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9
Q

acute inflammation (neutrophils)

A

IL-1, IL-6, TNF-alpha

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10
Q

netrophil extravasation

A

rolling, tight binding, diapedesis, migration

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11
Q

neutrophil chemotaxis

A

IL-8, LTB4, C5a, kallikrein

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12
Q

types of collagen mnemonic

A

“strong, slippery, stretchy, BM”

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13
Q

type 1 collagen

A

strong: bone, skin, dentin, scar tissue

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14
Q

type II collagen

A

slippery: cartilage, vitreous body, nucleus pulposus

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15
Q

type III collagen

A

stretchy: blood vessels, skin, uterus, fetal tissue, granulation tissue, reticular fibers

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16
Q

type IV collagen

A

BM: basement membrane

Board Review (11 decks)

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