Formed Elements Flashcards
Erythrocytes (RBC)
CD235a
Biconcave, anuclear
transport O2 and CO2
4.2-6 million, 100-120 days
Thrombocytes (platelets)
CD41, CD61, CD62
Fragments, anuclear
Thrombosis
150,000-500,000, 10 days
Megakaryocyte
Large multinucleate
Precursor of platelets
Neutrophils
AKA PMNS
CD66
Multilobed nucleus
Phagocytosis, intracellular killing with enzymes (O2 dependent or independent)
60%, 7-10 hr in blood, 3 days in tissue
Eosinophil
Bilobed nucleus, pink
Anti-parasite and extracellular killing
Around 4%, 18 hrs in blood, <2 weeks in tissue
Basophil
Bilobed nucleus
Allergies and anaphylaxis, bind IgE
1-2 years, <1%
Mast cells
Many granules
Allergies and anaphylaxis, bind IgE
60 hrs
Monocyte
CD14, CD33
8%, few days in blood
Become macrophage (in tissue) or DC
Kidney shaped nucleus
Macrophages
CD11c
Big eaters
(mononuclear phagocyte)
Last weeks in tissue
DC
CD11c
Antigen presenting cell
(mononuclear phagocyte)
Lymphocytes
27% WBCs, length varies
Adaptive immunity