Formative Exam Flashcards

1
Q

What does aetiology mean

A

The cause of disease

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2
Q

Experimental learning is what

A

Process of learning through experience

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3
Q

ICE stand for what

A

Ideas, concern and expectation

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4
Q

The more double bonds the less flexible a membrane is, true or false

A

False, makes it more flexible

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5
Q

Where is the primary site of respiration

A

Mito

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6
Q

Where does the buffer sit in the Henderson hasslebatch equation

A

Top denominator

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7
Q

What is experimental learning

A

Anything which engages your brain and makes you interact with learning material

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8
Q

What is the % of the human body is water

A

60%

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9
Q

The plasma membrane is full of ECM. What is a result of lack of dystrophin protein

A

Duchennes muscular dystrophy

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10
Q

How is odema caused

A

Lack of proteins due to liver failure, intestinal disease, starvation or necrosis. Lack of colloid osmotic pressure there what only moves out resulting in swelling = odema

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11
Q

Life span of platelets, neutrophils, macrophage, red

A

10 days,
10 hours
72 hours as monocytes, 3 months a macrophage
120 days

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12
Q

Explain synthesis and degradation of glycogen

A

Glucose to glucose 6-phosphate to glucose 1 phosphate by glycogenin. Primer formed and debranching enzymes act
Glycogen to glucose 1 phosphate by glycogen phosphotase which is then easily converted to glucose

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13
Q

Pepek mice have a mutation causing an increase in what enzyme

A

Pep carboxykinase
It results in increase gluconeogensis
Oxacloacete to PEP.

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14
Q

What is the enzyme which converts pyruvate to acetyl CoA

A

Pyruvate dehydrogenase

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15
Q

Cholesterol synthesis is regulated by the concentration of Actul CoA true or false

A

Regulated by HMG CoA reductase

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16
Q

Is a coenzyme protein or non protein

A

Non protein

17
Q

How many amino acids are synthesised by our body

A

11/20

18
Q

What do uncoupling agents do

A

Still allow electrons along the membrane but make the membrane permeable to H so the proton gradient is not established
Water is still formed but ATP is released as heat

19
Q

Urine test detects acetoacetate ?

A

True
Beta hydroxybutyrate detected by blood sample
Acetone exhaled

20
Q

3 main steps of oxidation

A

Fatty acid activation
Carnitine shuttle
Degradation - dehydrogenation, hydration, dehydrogenation, thiolysis

21
Q

What is capacitance in membrane potential

A

Capacitance is the electricity charging up membrane

22
Q

What are non specific ion channels permeable to

A

Any ion with a charge +1

When open Na+ move in causing depolarisation

23
Q

Where does sympathetic originate

A

12 thoracic and 2 lumbar

24
Q

How is nitrogen transferred between amino acids

A

Oxidative deaminatino and transamination between glutamate

25
Q

What amino acid can get nitrogen directly from ammonia

A

Glutamate

26
Q

What is nitrogen from body proteins transported from plasma to liver as

A

Glutamine

Or from skeletal muscle as alanine