Formative Exam Flashcards
What does aetiology mean
The cause of disease
Experimental learning is what
Process of learning through experience
ICE stand for what
Ideas, concern and expectation
The more double bonds the less flexible a membrane is, true or false
False, makes it more flexible
Where is the primary site of respiration
Mito
Where does the buffer sit in the Henderson hasslebatch equation
Top denominator
What is experimental learning
Anything which engages your brain and makes you interact with learning material
What is the % of the human body is water
60%
The plasma membrane is full of ECM. What is a result of lack of dystrophin protein
Duchennes muscular dystrophy
How is odema caused
Lack of proteins due to liver failure, intestinal disease, starvation or necrosis. Lack of colloid osmotic pressure there what only moves out resulting in swelling = odema
Life span of platelets, neutrophils, macrophage, red
10 days,
10 hours
72 hours as monocytes, 3 months a macrophage
120 days
Explain synthesis and degradation of glycogen
Glucose to glucose 6-phosphate to glucose 1 phosphate by glycogenin. Primer formed and debranching enzymes act
Glycogen to glucose 1 phosphate by glycogen phosphotase which is then easily converted to glucose
Pepek mice have a mutation causing an increase in what enzyme
Pep carboxykinase
It results in increase gluconeogensis
Oxacloacete to PEP.
What is the enzyme which converts pyruvate to acetyl CoA
Pyruvate dehydrogenase
Cholesterol synthesis is regulated by the concentration of Actul CoA true or false
Regulated by HMG CoA reductase
Is a coenzyme protein or non protein
Non protein
How many amino acids are synthesised by our body
11/20
What do uncoupling agents do
Still allow electrons along the membrane but make the membrane permeable to H so the proton gradient is not established
Water is still formed but ATP is released as heat
Urine test detects acetoacetate ?
True
Beta hydroxybutyrate detected by blood sample
Acetone exhaled
3 main steps of oxidation
Fatty acid activation
Carnitine shuttle
Degradation - dehydrogenation, hydration, dehydrogenation, thiolysis
What is capacitance in membrane potential
Capacitance is the electricity charging up membrane
What are non specific ion channels permeable to
Any ion with a charge +1
When open Na+ move in causing depolarisation
Where does sympathetic originate
12 thoracic and 2 lumbar
How is nitrogen transferred between amino acids
Oxidative deaminatino and transamination between glutamate
