Foot & Ankle Disorders

Question 1

Gout

Answer 1

1.) Disorder of the purine metabolism where hyperuricemia leads to deposition of sodium monourate crystals into cartilage, synovium and subcutaneous tissue2.) Male 20:1 predominance3.) Ages 40-604.) Crystals (tophi) evoke a strong inflammatory arthritis5.) First metatarsophalangeal joint is common first site6.) Laboratory test shows elevated: a.) ESR = Erythrocyte Sedimentation Rate b.) Leukocytosis = An abnormal increase in the number of circulating WBC’s c.) Hyperuricemia = Abnormal increase of uric acid levels in the blood7.) Diet high in organ meats and/or red wine