Foot and Ankle Flashcards
Foot and Ankle Primary Care
Diagnosis, Treatment, and When to Refer
Inside Each Foot There Are
- 26 _____
- 33 _____
- 19 _____
- 10 ____ 107 ________
- 26 bones
- 33 joints
- 19 muscles
- 10 tendons 107 ligaments
Foot Anatomy
Nail Anatomy
Diagnostic Tests for Foot, Ankle, Nail Abnormalities
(4)
Periodic Acid-Schiff (PAS) Reaction
Gomori Methenamine Silver (GMS) Stain
Fontana Masson Stain
PCR Assay (Molecular Genetic Testing)
Periodic Acid-Schiff (PAS) Reaction
Best for (1)
Most often does as (1)
- How does this test work?
- Reacts with most but not all (2)
- Sensitivity?
Best for superficial skin/nail infections, which do not disclose abundant acute inflammation
Routine Exam
- Chemical reaction, whereby carbohydrates are oxidized to form aldehydes → Aldehydes react with Schiff reagent to produce a magenta color
- Reacts with most fungi and yeast, shows excellent fungal morphology
- High sensitivity (few false negatives), but rarely organism specific
Gomori Methenamine Silver (GMS) Stain
Better for (1)
(1) Sensitivity when done with (1)
- How does it work?
- Stains most but not all (2)
- Sensitivity vs. morphology?
Better for Fungal Infections found in association with abscesses, better visualization of fungal infections in the deep tissues
High Sensitivity when done with PAS (but not organism specific)
- Stains carbohydrates (sugars), tissue is pre-treated with chromic acid, then silver is applied
- Stains most but not all fungi and yeast, may excel at staining degenerated organisms
- Offers high sensitivity, but poor morphology (target acquires a “dirty” granular appearance”
Fontana Masson Stain
Best used for (1)
Adds what to sensitivity?
- Highlights _____ pigment in fungal organisms
- Large quantities of melanin pigment favors dematiaceous ____ (pigmented saprophytic mold)
- Deciphers _____ pigment from other pigments (hemosiderin)
Validates the presence of an underlying melanocytic process, e.g. benign matrical melanotic macule, nevus, or melanoma
Adds specificity (identifies dematiaceous fungi) and screens for pigmented lesions within nail matrix
- Highlights melanin pigment in fungal organisms
- Large quantities of melanin pigment favors dematiaceous fungi (pigmented saprophytic mold)
- Deciphers melanin pigment from other pigments (hemosiderin)
PCR Assay (Molecular Genetic Testing)
What does this test do?
Sensitivity?
- If detected, g____ specific for the pathogens genus +/- species are sought
- Offers 2-3 day turn-around-time, rather than 28 days via c_____
- As a clinical lab test (such as bloodwork), molecular genetic studies are often paid for in-full by insurers
- Organism identification may be necessary for preauthorization of new topical nail antifungal products (indicated against Trichophyton Spp only)
- Augments the superior sensitivity of PAS/GMS, by providing high ______ (______ identification) for tar_____ patient therapy
Detects the genetic material of the pathologic fungi (dermatophytes, saprophytes, and/or yeasts)
Compared to culture, offers 25% higher sensitivity than culture overall, and twice its sensitivity when detecting dermatophytes
- If detected, genes specific for the pathogens genus +/- species are sought
- Offers 2-3 day turn-around-time, rather than 28 days via culture
- As a clinical lab test (such as bloodwork), molecular genetic studies are often paid for in-full by insurers
- Organism identification may be necessary for preauthorization of new topical nail antifungal products (indicated against Trichophyton Spp only)
- Augments the superior sensitivity of PAS/GMS, by providing high specificity (organism identification) for targeted patient therapy
What condition is shown in this picture?
Onychomycosis
Onychomycosis is a fungal infection of the toenails or fingernails that may involve any component of the nail unit, including the matrix, bed, or plate. Onychomycosis can cause pain, discomfort, and disfigurement and may produce serious physical and occupational limitations, as well as reducing quality of life
Mimics of Onychomycosis
What condition is shown in these pictures?
Mimics of Onychomycosis
What condition does this picture show?
Symptoms
- p____ under nail
- l_____ nail
Cause
- pressure or imp____ to toenail
- bl_____ under nail causes discoloration
Intervention
- Acute dec______ if severe pain
- Leave it _____
Subungual Hematoma
Symptoms
- pain under nail
- loose nail
Cause
- pressure or impact to toenail
- bleeding under nail causes discoloration
Intervention
- Acute decompression if severe pain
- Leave it alone
Antifungal Medications
Warts
What type of Warts are shown in these pictures?
Verruca Plantaris (left pic)
Verruca Plantaris (Mosaic) (right pic)
H&E Verruca
Treatment for Warts
Topicals/Orals
- S____ Acid
- Candida injections
- Can____
- Ret_____ Creams
- 5-__
- Bleo_____ injections
- I______therapy
- Cim_____
- Salicylic Acid
- Candida injections
- Canthrone
- Retinoid Creams
- 5-FU
- Bleomycin injections
- Immunotherapy
- Cimetidine
Treatment for Warts
Surgery/Modalities
- C____therapy
- Pulse D___ La___
- C____tage + Hyfercation
- Cryotherapy
- Pulse Dye Laser
- Curettage + Hyfercation
Mimics of Verucca
What condition is shown in this picture?
Treatment
- De_______ (frequent)
- (1) with padding or orthoses
Intractable Plantar Keratosis (IPK)
Treatment
- Debridement (frequent)
- Offloading with padding or orthoses
IPK is caused by a “dropped metatarsal,” which happens when the metatarsal head drops to a lower level than the surrounding metatarsals and protrudes from the bottom of the foot. This results in more pressure being applied in this area and causes a thick callus to form.
Inflammation of the fingers or toes in one or more of the three nail folds. Acute form is caused by polymicrobial infections after the protective nail barrier has been breached
Paronychia
Paronychia Treatment
Acute
- __ ABX
- _______ ABX
- Home S____
- Surgical De_______
Chronic
- Phenol/Al____ Chemical Matrix______
- Sur___ Matrix_____
Acute
- PO ABX
- Topical ABX
- Home Soaks
- Surgical Decompression
Chronic
- Phenol/Alcohol Chemical Matrixectomy
- Surgical Matrixectomy
Is an inflammation of the sesamoid bones in the ball of the foot and the tendons they are embedded in. It’s usually caused by overuse, especially by dancers, runners and athletes who frequently bear weight on the balls of their feet. It’s treated with rest and anti-inflammatory medication
Is a condition in which the ball of your foot becomes painful and inflamed. You might develop it if you participate in activities that involve running and jumping. There are other causes as well, including foot deformities and shoes that are too tight or too loose
Sesamoiditis
Metatarsalgia
Sesamoiditis or Metatarsalgia
-
Symptoms
- P____
- Sw_____ at ball of foot
-
Causes
- Imp____ → Inf____
- Fr______ sesamoid
-
Intervention
- Rest or Off_____
- I__
- C_______
- E_____
- P____ control
-
Symptoms
- Pain
- Swelling at ball of foot
-
Causes
- Impact → Inflammation
- Fractured sesamoid
-
Intervention
- Rest or Offloading
- Ice
- Compression
- Elevation
- Pain control
Puncture wound/Foreign Body
Foreign body may either still be present or just puncture wound
Intervention (1)
Call someone who has experience as situation may complicated
Athletes foot, fungal skin infection
White, scaling plaques in a moccasin distribution
Tinea Pedis
Tinea Pedis Treatment
- (1) for 2-4 weeks
- Add topical (1) if very itchy or pustular
- Topical antifungal cream, lotion or foam for 2-4 weeks
- Add topical steroid if very itchy or pustular