Food and Water borne Flashcards

1
Q

5 Food and waterborne disease in Malaysia

A
Typhoid
• Cholera
• Food poisoning
• Dysentery
• Hepatitis A
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2
Q

Bacteria species food

A
Salmonella spp, 
Shigella spp, 
Vibrio cholera,
Escherichia coli, 
Listeria monocytogenes, Clostridium
sp
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3
Q

Fungi species food

A

Candida spp,

Sporothrix spp

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4
Q

Virus species food

A

Hepatitis A, Adenovirus, Norovirus, Rotavirus

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5
Q

Parasites species food

A

Entamoeba histolytica, Giardia

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6
Q

Water-borne diseases:

A
  • Typhoid fever
  • Cholera
  • Hepatitis A
  • Leptospirosis
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7
Q

Salmonella dose

A

Higher dose up to 10,000 -1,000,000 organisms per gram to cause infection

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8
Q

Causes of salmonella

A

inadequate cooking, thawing
cross contamination
vectors

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9
Q

Typhoid causative agent

A

salmonella typhi

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10
Q

Why Typhoid still ongoing?

A
  • Healthy Carrier
  • Cases have not been clean-up
  • Personal Hygiene
  • Vaccination for food handler
  • Food Premises
  • Sanitation/Water supply
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11
Q

Who are at

risk of typhoid (4)

A

Children
Travellers to endemic areas
Occupation related
Immunocompromised

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12
Q

types of typhoid outbreak (4)

A

Sporadic -
involving only one or two persons in a household

Family outbreaks -
several members of the family are affected

Large outbreaks
caused by a widely distributed infective food item

Institutional outbreaks -caused by a contaminated single food item

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13
Q

Typhoid incubation

A

2 weeks, but might vary between 3-28 days

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14
Q

typhoid symptoms/ complications

A
  • Fever, headache, constipation, bradycardia
  • complication: intestinal perforation, chronic carrier

The abdominal symptoms are severe
Fever and illness may
continue for 4-6 weeks

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15
Q

characteristics of a typhoid carrier

A

• Persistent positive stool culture for Salmonella
typhi for a year after the onset of acute typhoid
fever
• transmit infection to others
• Carrier state: 15% of patients, depending on age,
become chronic carriers harbouring S.typhi in the
gallbladder

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16
Q

Management of Typhoid

A

Notification: Malaysian Act 342
• Hygienic control of food and water supplies
• Detection and treatment of chronic carriers
• Vaccination.

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17
Q

cholera species that cause diarrhoea

A

 Inaba

 Ogawa

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18
Q

dosage for infection, cholera

A

small

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19
Q

method of action, cholera

A

multiplies in small intestine, makes toxins. isotonic fluid leaves into lumen of bowel

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20
Q

symptoms of cholera

A
Rice-watery stool-severe
• Dehydration
• With/without vomiting
• Muscle cramps
• Hypovolemic shock
• Scanty urine
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21
Q

management of cholera

A

Rehydration
• Monitor vital signs-blood pressure/pulse rate/urine output
• Antibiotic-for severe cases
• Proper sewage disposal/ good personal hygiene
• Proper cooking and hygienic handling of food
• Vaccination

22
Q

Dysentery causes

A

wht• Shigella spp
• Entamoeba histolytica
• Escherichia coli O157

23
Q

what is dysentery

A

blood mucus-rich diarrhoea

24
Q

Shigella spp- dose

25
Shigella spp- lifespan
long term, in tap water 6 months, sea water 2-5 month
26
Shigella shigellosis symptoms
Frequent passage of scanty amount of stools, mostly mixed with blood and mucus • Moderate to high grade fever • Severe abdominal cramps • Tenesmus– pain around anus during defecation
27
Shigella spp-diagnosis
``` Clinical Microbiological investigations • specimen: stool/blood • test: Microscopic/macroscopic • identification of bacteria: biochemical test ```
28
Escherichia coli- food species
Enteropathogenic E. coli (EPEC), Enterotoxigenic E. Coli (ETEC), Enteroinvasive E. coli (EIEC) Enterohemorrhagic E. coli (EHEC)
29
Enterohemorrhagic E. coli- symptoms and duration; complications
hemorrhagic colitis: diarrhoea, abdominal pain, vomiting. lasts for 4 - 8 days, may extend to 13 days. Complications: bloody diarrhoea, acute ulcerative or ischemic colitis and sub-mucosal edema with severe colonic inflammation
30
What is special about E. coli O157:H7
heat sensitive but rsistant to freezing - cook your food
31
what is hemolytic uremic syndrome (HUS)
E coli 0157 leading to acute renal failure, microangiopathic hemolytic anemia and thrombocytopenia
32
Entamoeba histolytica cause, who does it affect, what's different about it
cyst on hands usually elderly chronic in nature more mucus, less blood in stools; stools are very offensive and bulky
33
Laboratory diagnosis -Entamoeba
Stool Examination: Saline – motile trophozoites with ingested RBCs Iodine – body stains yellow, nucleus with a central karyosome, brown glycogen mass
34
Food poisoning symptoms
Acute onset of vomiting and / or diarrhoea and / or other symptoms associated with ingestion of contaminated food. neurological symptoms: motor weakness and cranial nerve palsies.
35
food poisoning species
Staphylococcus aureus, Bacillus cereus, Listeria | monocytogenes, Clostridium spp
36
Staphylococcus aureus bacteria type, growth range
non spore forming, gram negative grows at a range temperature between 12-44C (optimum 37C) pH range 4.0-9.83 (optimum 7.4-7.6)
37
Symptoms, incubation of staph aureus
1-6 hours | nausea, headache, vomiting, diarrhoea
38
Bacillus cereus mechanism, food and symptoms
Spore forming gram positive rods consumption of enterotoxins slow cooled rice, improper reheat Fever, diarrhoea, vomiting
39
Bacillus presentation
Good hygiene Proper cooking of foods to destroy spores Keep food at low temperature Fast cooling of food
40
Listeria monocytogenes features
Gram positive bacterium pathogenic to animals and human Able to survive for many years in the cold in naturally infected sources Faecal carriage 1-5% of healthy people Trans-placental spread from mother to neonate
41
Listeria symptoms
Abortion in pregnant women Meningitis in newborn infants and immunocompromised adults. Risk: Pregnant women, infants and elderly people. Deaths have been reported in fetuses, neonates and other individuals with compromised health status.
42
Clostridium perfringens features
spore-forming, anaerobic, gram positive bacillus enterotoxin Bacteria is found in the soil, dust, water, sewage marine sediments, decaying cooling causes toxin growth, food cooked one day served the next
43
Botulism features
Enterotoxins produced by Clostridium botulinum. C. botulinum is an obligate, spore-forming anaerobe, and Gram positive bacilli Neurotoxins, that are highly toxic, heat labile (inactivated by heating at 80oc for 10 min) Unstable at alkaline pH, resistant to pepsin and acidic environment. Resist the action of the gastric and intestinal juices. Fucking lethal incubation period: 12-72 H Neuro symptoms 1-10 days duration
44
fungal intoxication
from metabolites, mycotoxins, mproper drying before storage
45
complications of food poisoning
* Dehydration * Electrolyte imbalances * Tetany * Convulsions * Hypoglycemia * Renal failure
46
Viral food borne infections features
acid resistant, attacks certain lining cells in GIT to replicate, High virus content in fecal matter
47
Hep A
30 day incubation | long lasting
48
rotavirus
green shit, gradual onset, kids 1-2, fever
49
general investigation of FBD
``` Stool microscopy &Stool cultures Blood cultures ELISA for rotavirus Immunoassays, bioassays or DNA probe tests to identify E. coli strains Detection of toxins ```
50
management of FBD
``` Symptomatic treatment • Rehydration • Antipyretic • Anti-emetic • Antibiotic for severe cases ```
51
vaccines
Vaccine is available for • Typhoid • Cholera • Hepatitis A