FOLLICULOGENESIS Flashcards

1
Q

Oogenesis involves two maturation processes happening at once what are those processes?

A

the maturation of the ovum and the maturation of the ovarian follicle or foliculogenesis

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2
Q

is the developmental process of ovarian follicles starting from a reserve of quiescent primordial follicles set up in early life and ending with either ovulation or follicular death by atresia

A

Folliculogenesis

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3
Q

Folliculogenesis is the developmental process of ovarian follicles starting from a reserve of quiescent primordial follicles set up in early life and ending with either?

A

ovulation or follicular death by atresia

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4
Q

is a roughly spheroid cellular aggregation set of somatic ells which is the basic units of the female reproductive biology containing a single oocyte

A

OVARIAN FOLLICLE

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5
Q

are the first class of follicles formed in mammalian ovaries

A

primordial follicles

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6
Q

primordial follicles are the first class of follicles formed in mammalian ovaries and consist of a?

A

primary oocyte

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7
Q

primordial follicles are the first class of follicles formed in mammalian ovaries and consist of a primary oocyte surrounded by a?

A

single layer of flattened granulosa cells

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8
Q

These follicles remain in a dormant state until they receive signals for activation or are relieved of a negative regulatory factor

A

primordial follicles

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9
Q

When the primordial follicle is stimulated, it becomes a?

A

primary follicle

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10
Q

In primary follicle the primary oocyte ?, and the follicular cells ?

A

enlarges and divide

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11
Q

follicle that has two layers of follicular cells is called?

A

primary follicle

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12
Q

These cells continue to hypertrophy and proliferate to form many layers surrounding the oocyte.

A

primary follicle

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13
Q

transition from a primordial follicle to a primary follicle, the flattened cells surrounding the oocyte (called pre-granulosa or follicular cells) change in shape and function. They grow larger and become cuboidal in shape, at which point they are officially referred to as?

A

granulosa cells

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14
Q

during the transition from a primordial follicle to a primary follicle, the ?, a thick glycoprotein layer, begins to develop between the oocyte and the surrounding granulosa cells.

A

zona pellucida

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15
Q

during the transition from a primordial follicle to a primary follicle, the stroma surrounding the follicle begins to develop and form a structure known as the?

A

theca

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16
Q

Only one of the maturing follicles completes the maturation process each month. The rest degenerate into?

A

atretic follicles

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17
Q

primary follicle develops into?

A

secondary follicle

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18
Q

Looks very similar to primary follicles, except that they are larger, there are more follicular cells, and there are small accumulations of fluid in the intracellular spaces called follicular fluid (nutritive fluid for the oocyte)

A

secondary follicles

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19
Q

secondary follicles look very similar to primary follicles, except that they are larger, there are more follicular cells, and there are small accumulations of fluid in the intracellular spaces called?

A

follicular fluid

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20
Q

What is the name of the fluid-filled cavity that forms as small pockets of fluid within a secondary follicle gradually coalesce?

A

Antrum

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21
Q

the surrounding granulosa cells of secondary follicle is called?

A

cumulus oophorus

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22
Q

What are the surrounding theca of secondsry follicle that differentiates into two layers:

A

• Theca interna
• Theca externa

23
Q

This theca surround the granulosa cells and a rounded cells that secrete androgens and follicular fluid

A

Theca interna

24
Q

This theca is a,more fibrous spindle shaped cells

A

Theca externa

25
The androgens are converted into ? by the granulosa cells pf secondary follicle
estrogen
26
The secondary follicle develops into?
Graffian follicle
27
after the first meiotic division of the secondary oocyte, most of the cytoplasm is indeed retained in?
one of the two daughter cells
28
After the first meiotic division, most of the cytoplasm goes into one of the two daughter cells. The other becomes the?
polar body
29
The follicular fluid fills a single space, called the antrum, which is surrounded by the follicular cells - called the?
membrana granulosa
30
The granulosa cells of graafian follicle that surrounds the oocyte, and project into the antrum are called as the?
cumulus oophorus
31
This follicle contains a secondary oocyte which was arrested in metaphase 2 and completes it's meiosis shortly before ovulation resulting to a secondary oocyte and a polar body.
Graafian Follicle
32
The secondary oocyte together with the zona pellucida and corona radiata will be released from the follicle during?
ovulation
33
It is a thick layer of glycoproteins present around the plasma membranes of oocytes.
ZONA PELLUCIDA
34
A thickened mound of granulosa cells that surround the oocyte and projects into the antrum of the ovarian follicles.
CUMULUS OOPHORUS ("Egg-bearing heap").
35
It is the innermost layer of cumulus cells, immediately adjacent to the Zona Pellucida. Cells in this layer extend their cytoplasm toward the oocyte through the Zona Pellucida.
CORONA RADIATA
36
It is the layer of granulosa cells ( follucular cells ) bordering the antrum
Membrana granulosa
37
The fuid (LIQUOR FOLLICULI) filled space of an ovarian follicle which is present in the secondary and tertiary follicles.
ANTRUM
38
It is an accumulation of granulosa cells connecting the granulosa cells surrounding the oocyte with the peripheral granulosa cells layer in a Grafian follicle.
HILLOCK
39
These cells are endocrine-like and border the membrana granulosa. The function in the production of estrogen
Theca interna
40
Fibroblast-resembling cells just outside the theca interna. It's exterior limits are not discernible because it blends and merges with other cells of the ovarian stroma; the beginning of this layer can be identified, however, by its proximity to the theca interna.
THECA EXTERNA
41
A fully mature Graafian follicle ruptures and releases the female gamete in a phenomenon known as?
ovulation
42
The secondary oocyte, zona pellucida and the corona radiata are all expelled at ovulation, and enter the?
fallopian tube
43
Once released, the secondary oocyte begins its second meiotic division, as far as metaphase Il. Division only carries on if the ovum is?
fertilized
44
Also called the bleeding corpus luteum
CORPUS HEMORRHAGICUM
45
Itis a temporary structure formed immediately after ovulation from the ovarian follicle as it collapses and is filled with blood that quickly clots.
CORPUS HEMORRHAGICUM
46
is the transitional stage between the Dominant folicle and Corpus Luteum.
Corpus Hemorrhagicum
47
is made up of lutein cells (from the Latin luteus, meaning "saffron-yellow"), which develop immediately following ovulation, when yellow pigment and lipids accumulate within the granulosa cells lining the follicle.
corpus luteum
48
corpus luteum secretes?
estrogens and progesterone
49
If the egg is not fertilized, the corpus luteum becomes inactive after? And what occurs?
10-14 days, and menstruation occurs
50
It is the regressed form of the corpus luteum
CORPUS AL BICANS
51
What are cells that help clean up and remove the old tissue of corpus luteum
Macrophages
52
These cells lay down type / collagen, forming the corpus albicans.
Fibroblasts
53
As the corpus luteum is being broken down by macrophages, fibroblasts lay down type / collagen, forming the corpus albicans. This process is called?
utelysis
54
The remains of the ? may persist as a scar on the surface of the ovary
corpus albicans