FOLLICULOGENESIS Flashcards
Oogenesis involves two maturation processes happening at once what are those processes?
the maturation of the ovum and the maturation of the ovarian follicle or foliculogenesis
is the developmental process of ovarian follicles starting from a reserve of quiescent primordial follicles set up in early life and ending with either ovulation or follicular death by atresia
Folliculogenesis
Folliculogenesis is the developmental process of ovarian follicles starting from a reserve of quiescent primordial follicles set up in early life and ending with either?
ovulation or follicular death by atresia
is a roughly spheroid cellular aggregation set of somatic ells which is the basic units of the female reproductive biology containing a single oocyte
OVARIAN FOLLICLE
are the first class of follicles formed in mammalian ovaries
primordial follicles
primordial follicles are the first class of follicles formed in mammalian ovaries and consist of a?
primary oocyte
primordial follicles are the first class of follicles formed in mammalian ovaries and consist of a primary oocyte surrounded by a?
single layer of flattened granulosa cells
These follicles remain in a dormant state until they receive signals for activation or are relieved of a negative regulatory factor
primordial follicles
When the primordial follicle is stimulated, it becomes a?
primary follicle
In primary follicle the primary oocyte ?, and the follicular cells ?
enlarges and divide
follicle that has two layers of follicular cells is called?
primary follicle
These cells continue to hypertrophy and proliferate to form many layers surrounding the oocyte.
primary follicle
transition from a primordial follicle to a primary follicle, the flattened cells surrounding the oocyte (called pre-granulosa or follicular cells) change in shape and function. They grow larger and become cuboidal in shape, at which point they are officially referred to as?
granulosa cells
during the transition from a primordial follicle to a primary follicle, the ?, a thick glycoprotein layer, begins to develop between the oocyte and the surrounding granulosa cells.
zona pellucida
during the transition from a primordial follicle to a primary follicle, the stroma surrounding the follicle begins to develop and form a structure known as the?
theca
Only one of the maturing follicles completes the maturation process each month. The rest degenerate into?
atretic follicles
primary follicle develops into?
secondary follicle
Looks very similar to primary follicles, except that they are larger, there are more follicular cells, and there are small accumulations of fluid in the intracellular spaces called follicular fluid (nutritive fluid for the oocyte)
secondary follicles
secondary follicles look very similar to primary follicles, except that they are larger, there are more follicular cells, and there are small accumulations of fluid in the intracellular spaces called?
follicular fluid
What is the name of the fluid-filled cavity that forms as small pockets of fluid within a secondary follicle gradually coalesce?
Antrum
the surrounding granulosa cells of secondary follicle is called?
cumulus oophorus