Fluoride Flashcards
Fredrick McKay
discovered brown stain
coined term “mottled enamel”
determined water was the cause
HV Churchill
chemist
fluorine caused enamel change
used McKay’s findings
Fluoride
- latin word Fluere meaning flow
- discovered in 1886 by Henri Moissan
- atomic element #9
Absorption
GI tract –> passive diffusion, absorbed within 1 hour, less absorption when taken with milk and food
Blood Stream –> plasma is the carrier, maximum levels reached within 30 mins, normal levels are low, levels constantly fluctuating
Fluoride Distribution
- 99% of fluoride is in mineralize tisues
- crystal lattice of teeth (small amounds IN teeth, higher amounts ON teeth)
Excretion
- most excreted via kidneys in the urine
- small amounts by sweat and feces
- limited transfer from plasma to breast milk for excretion by that route
Pre-Eruptive: Mineralization Stage
- fluoride reaches fetus by way of surrounding blood plasma
- risky in that excess fluoride may lead to fluorosis - hypomineralization, stops ameloblasts; only occurs during development
- beneficial in that teeth develop more shallow grooves
Pre-Eruptive: Maturation Stage
-absorbed from surrounding tissues
Post-Eruptive
- obtained from water, dentifrice, rinses
- prevents caries
- rapid uptake during first years after eruption
- fluorosis is not possible once tooth development is complete
Dentin
- fluoride is greater in exposed dentin than in enamel
- higher concentration at pulp where exchange takes place
- newly formed dentin absorbs fluoride rapidly
Biofilm/Saliva
- may contain 5-50ppm fluoride
- fluoride remineralizes teeth by attracting calcium and phosphate
- inhibits demineralization (pH < 5.5)
Caries Diagnosis and Management
-can be sealed up to moderate lesion ICDAS 3
ICDAS 0 to ICDAS 6
Remineralization
- saliva neutralizes acids
- mineral replacement
- arrests caries
- white spots harden/hypermineralize
Norfolk
optimal fluoride level 0.90 mg/L
Topical Effects of Fluoride Preventing Caries
- inhibit demineralization
- enhance remineralization of incipient lesions
- inhibit bacterial activity by inhibiting enolase, an enzyme needed by bacteria to metabolize carbohydrates